Natural Aging of Biomaterials in Ambient and Physiological Environments
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley +1 more source
Enzymatic Encoding of Topology in an Intrinsically Disordered Single‐Chain Protein
Enzymatic intramolecular cross‐linking enables topology control in intrinsically disordered proteins, yielding SCNPs with reproducible cavity architectures. Using β‐casein and microbial transglutaminase, sparse, sequence‐resolved constraints drive compact collapse without inducing secondary structure.
Joshua Johani +9 more
wiley +2 more sources
Development of a Numerical Model of a Bio-Inspired Sea Lion Robot. [PDF]
Kadapa S +4 more
europepmc +1 more source
Bowl‐shaped Janus nanomotors with platinum, iron oxide, and polypyrrole integrate catalytic, magnetic, and electric propulsion for targeted drug delivery. They demonstrate controlled, directional motion under varying pH and hydrogen peroxide conditions, with optimal performance in neutral media.
Kimia Tavakoli Dehaghi +3 more
wiley +1 more source
Mechanically strong and highly conductive graphitized carbon nanowire arrays for nano-fabrication of carbon-based chips. [PDF]
Deng J, Liu C, Chen X, Madou M.
europepmc +1 more source
Computational fluid dynamics-based flow field simulation and optimization of negative-pressure stone removal: stone size, position, and sheath geometry. [PDF]
Tian C +6 more
europepmc +1 more source
CSAKD: Determining Absolute Ligand Affinities From 19F NMR Chemical Shift Anisotropy
Affinity determination is crucial in drug discovery, yet remains difficult for weakly binding fragments. We introduce chemical shift anisotropy KD$K_{\text{D}}$ (CSAKD) by 19F$^{19}{\rm F}$ NMR relaxation experiments, a titration‐free method that requires no isotopic labeling.
Simon H. Rüdisser +2 more
wiley +1 more source
AI-Resolved Protein Energy Landscapes, Electrodynamics, and Fluidic Microcircuits as a Unified Framework for Predicting Neurodegeneration. [PDF]
Pantu C +8 more
europepmc +1 more source
Electrochemically Triggered Supramolecular Polymerization Under Kinetic Control
Chemical and electrochemical stimuli enable controlled supramolecular polymerization of perylene diimide–histidine (PDI–His). Redox processes mediate the transformation of kinetically trapped aggregates into thermodynamically stable nanofibers, thereby supporting seeded growth. This approach provides a strategy for regulating self‐assembly pathways and
Eun Gyu Lee +6 more
wiley +1 more source

