Results 201 to 210 of about 14,645,959 (297)
Hydrodynamics rather than water temperature shapes the macroinvertebrate communities in alpine rivers on the Qinghai-Xizang Plateau. [PDF]
Luo Y, Xu M, Zhou X, Li D, Fu X.
europepmc +1 more source
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang +6 more
wiley +1 more source
Automated Cerebrospinal Fluid Flow Quantification in Hydrocephalus Using Phase-Contrast Magnetic Resonance Imaging. [PDF]
Rodríguez Martínez EA +4 more
europepmc +1 more source
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu +7 more
wiley +1 more source
Influence of cross-sectional geometry on the wave attenuation performance of floating breakwaters: an experimental study. [PDF]
Ashraf A, Ezzeldin R, Saad ME.
europepmc +1 more source
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou +11 more
wiley +1 more source
An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer
Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li +11 more
wiley +1 more source
TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
Optofluidic Sensing and Sorting of Chiral Drugs Based on Core-Shell Composite Microspheres. [PDF]
Gao H, Yang W, Cao T.
europepmc +1 more source

