Results 81 to 90 of about 74,394 (308)

Hydrodynamic Regulation of Monocyte Inflammatory Response to an Intracellular Pathogen

PLoS ONE, 2011
Systemic bacterial infections elicit inflammatory response that promotes acute or chronic complications such as sepsis, arthritis or atherosclerosis. Of interest, cells in circulation experience hydrodynamic shear forces, which have been shown to be a potent regulator of cellular function in the vasculature and play an important role in maintaining ...
Shankar J Evani, Ashlesh K Murthy, Naresh Mareedu, Robbie K Montgomery, Bernard P Arulanandam, Anand K Ramasubramanian   +5 more
openaire   +4 more sources

Glucose Deprivation‐Driven Concurrent Induction of Apoptosis/Disulfidptosis/Ferroptosis by Tumor Targeting Nanoassemblies in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Innovative hybrid nanoassemblies installed with ferrocene, D‐α‐tocopherol succinate, and phloretin exploit the metabolic vulnerability of triple‐negative breast cancer under glucose starvation. By blocking glucose uptake, this single nanoplatform simultaneously orchestrates apoptosis, disulfidptosis, and ferroptosis to achieve synergistic and ...
Song Yi Lee, ChaeRim Hwang, Seong Eun Kim, Mrinmoy Karmakar, Seo Jin Jung, Hyeonseok Jang, Hae‐In Kim, Heejung Yang, Junmin Lee, Dae‐Duk Kim, Hyun‐Jong Cho   +10 more
wiley   +1 more source

Study of Groove Parameters on the Hydrodynamic Behavior of Spiral-Grooved Thrust Bearing with Gas Lubricant

International Journal of Rotating Machinery, 2021
The gas-lubricated thrust bearing is widely used in agriculture mechanical systems, and the groove shape plays an important role on the hydrodynamic behavior of spiral-grooved thrust bearing (SGTB).
Xianfei Xia, Yu Chen, Xiuying Wang, Yu Sun   +3 more
doaj   +1 more source

Ultrasensitive Detection of Porcine Epidemic Diarrhea Virus Infections Using Multivalent DNA Nanostructure‐Enabled Lateral Flow Assay

Advanced Healthcare Materials, EarlyView.
A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao, Akhila Naru, Dhanush Gandavadi, Mengxi Zheng, Saraswathi Lanka, Hyeongjun Cho, Chau Nguyen Minh Hoang, Jianqiang Zhang, Ying Fang, Xing Wang   +9 more
wiley   +1 more source

Standardized Effect Measures Informing Next‐Generation Strategies for Mechanical Stimulation in Cartilage Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This systematic review quantitatively compares conventional mechanical stimulation strategies in cartilage tissue engineering across 85 heterogeneous in vitro studies. Applying standardized effect measures, meta‐analysis reveals that combined compression and shear loading optimally promotes cartilage matrix development.
Jiaqi K. Shen, Tony B. Huang, Catherine E. Davey, Elias Salzer, Gerjo J. V. M. Van Osch, Sandra J. Shefelbine, Marcus G. Pandy, Kathryn S. Stok   +7 more
wiley   +1 more source

Experimental Study of Mooring Configuration Effects on the Hydrodynamic Response of a Hexagonal Rigid FPV Platform

Journal of Marine Science and Engineering
Maintaining structural stability and reliable mooring performance remains a key challenge for offshore floating photovoltaic (FPV) systems. This study investigates the coupled hydrodynamic and mooring behavior of a novel large-scale hexagonal rigid FPV ...
Haitao Li, Jijian Lian, Dongming Liu, Zheng Cao, Yong Li   +4 more
doaj   +1 more source

Improved VIV Response Prediction Using Adaptive Parameters and Data Clustering

Journal of Marine Science and Engineering, 2020
Slender marine structures such as deep-water riser systems are continuously exposed to currents, leading to vortex-induced vibrations (VIV) of the structure. This may result in amplified drag loads and fast accumulation of fatigue damage.
Jie Wu, Decao Yin, Halvor Lie, Signe Riemer-Sørensen, Svein Sævik, Michael Triantafyllou   +5 more
doaj   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source

Hydrodynamic response of viscous fluids under seismic excitation [PDF]

, 1993
Hydrodynamic response of liquid-tank systems, such as reactor vessels, spent-fuel pools and liquid storage tanks have been studied extensively in the last decade (Chang et al. 1988; Ma et al. 1991).
Ma, D. C.
core