Results 231 to 240 of about 636,209 (356)

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Water Parameters and Hydrodynamics in Rivers and Caves Hosting <i>Astyanax mexicanus</i> Populations Reveal Macro-, Meso- and Microhabitat Characteristics. [PDF]

Ecol Evol
Legendre L, Père S, Rebaudo F, Espinasa L, Attia J, Rétaux S.   +5 more
europepmc   +1 more source

Methodology to compute the speed of pumps that fit the hydrodynamic levels in a well field [PDF]

Sanda-Carmen Georgescu, Dragoş Găitănaru, Iulian Iancu, C Miron, Andrei-Mugur Georgescu   +4 more
openalex   +1 more source

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

Advanced Healthcare Materials, EarlyView.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova, Fatemeh Ahmadi, Jennifer Cruickshank, Zheyuan Miao, David W. Cescon, Eugenia Kumacheva   +5 more
wiley   +1 more source

An experimental insight of the hydrodynamics of microjet assisted fluidized bed of ultrafine particles. [PDF]

Sci Rep
Ali SS, Hossain SKS, Mohsin MEA, Asif M.
europepmc   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Quality Management of Inert Material During Fluidized Bed Combustion of Biomass. [PDF]

Materials (Basel)
Wesolowska M, Wisniewski K, Krzywanski J, Nowak W, Kijo-Kleczkowska A.   +4 more
europepmc   +1 more source

Ferritin‐Doped Nanoparticles Triggered Tumor‐Specific Darkening for Enhanced Photothermal Tumor Ablation and Immune Activation

Advanced Healthcare Materials, EarlyView.
Ferritin‐doped hybrid nanoparticles triggered accurate tumor‐specific hemorrhage for enhanced in situ photothermal therapy and evoked anti‐tumor immunity. Notably, HFn/GA‐Fe specifically induced tumor hemorrhage 12 h after intravenous injection, resulting in visible color darkening. Through photoacoustic imaging, tumor vessels could be clearly observed
Haidong Zha, Xiao Liang, Long Xi, Jiamao Chen, Wenzhao Zhong, Zhen Yuan, Meng Xu, Ying Zheng   +7 more
wiley   +1 more source

Shallow-lake sediments release nutrients by complete destratification events. [PDF]

J Environ Qual
Jan J, Breton F, Borovec J.
europepmc   +1 more source

Smooth Particle Hydrodynamics Simulation of Micro-Cup-Extrusion Using a Graphit-ic Coating [PDF]

, 2014
LI Shi-cheng, Zezhong Chen, Zheng Jie, Wang Dong-feng   +3 more
openalex   +1 more source