Results 51 to 60 of about 802,767 (303)

Neutral hydrogen absorption towards Fast Radio Bursts [PDF]

, 2015
If Fast Radio Bursts (FRBs) are truly at astronomical, in particular cosmological, distances, they represent one of the most exciting discoveries in astrophysics of the past decade.
Fender, Rob, Oosterloo, Tom
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

FUSE and HST STIS Observations of Hot and Cold Gas in the AB Aurigae System [PDF]

, 2001
We present the first observations of a Herbig Ae star with a circumstellar disk by the Far Ultraviolet Spectroscopic Explorer (FUSE), as well as a simultaneous observation of the star obtained with the Hubble Space Telescope Space Telescope Imaging ...
Andre, M., Boggess, A., Bouret, J. -C., Bruhweiler, F. C., Deleuil, M., Etangs, A. Lecavelier des, Feldman, P. D., Ferlet, R., Grady, C. A., Roberge, A., Vidal-Madjar, A., Woodgate, B.   +11 more
core   +3 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Hydrogen absorption study of ti-based alloys performed by melt-spinning

Materials Research, 2013
The hydrogen absorption and desorption of Ti53Zr27Ni20 icosahedral quasicrystal (ICQ) and Ti50Ni50 shape memory alloy (SMA) melt-spun ribbons was studied. Samples were exposed to hydrogen gas at 623 K and 4 MPa for 1000 minutes.
R.M. Ribeiro, L.F. Lemus, D.S. dos Santos   +2 more
doaj  

Damped Lyman-alpha Absorption Associated with an Early-Type Galaxy at Redshift z = 0.16377

, 1997
We report new HST and ground-based observations of a damped Lyman-alpha absorption system toward the QSO 0850+4400. The redshift of the absorption system is z = 0.163770 and the neutral hydrogen column density of the absorption system is log N = 19.81 cm*
Altan, Hakan, Barcons, Xavier, Chen, Hsiao-Wen, Fernandez-Soto, Alberto, Lanzetta, Kenneth M., Meyer, David, Ortiz-Gil, Amelia, Savaglio, Sandra, Webb, John, Wolfe, Arthur M., Yahata, Noriaki   +10 more
core   +1 more source

QSO 0130-4021: A third QSO showing a low Deuterium to Hydrogen Abundance Ratio [PDF]

, 1999
We have discovered a third quasar absorption system which is consistent with a low deuterium to hydrogen abundance ratio, D/H = 3.4 times 10^-5. The z ~ 2.8 partial Lyman limit system towards QSO 0130-4021 provides the strongest evidence to date against ...
Adams T. F., Carswell R. F., Dan Lubin, David Kirkman, David Tytler, John M. O’Meara, Levshakov S. A., Scott Burles   +7 more
core   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Molecular Hydrogen in Orion as Observed by the Far Ultraviolet Spectroscopic Explorer

, 2005
Diffuse far-ultraviolet stellar emission scattered by dust grains has been observed in a region near the Orion Nebula. In addition to the scattered stellar continuum, emission and absorption features produced by molecular hydrogen have been identified ...
France, K., McCandliss, S. R.
core   +1 more source

Physical Conditions in Orion's Veil [PDF]

, 2004
Orion's veil consists of several layers of largely neutral gas lying between us and the main ionizing stars of the Orion nebula. It is visible in 21cm H I absorption and in optical and UV absorption lines of H I and other species.
C. L. Brogan, C. R. O’Dell, G. J. Ferland, G. Shaw, Launay J. R., N. P. Abel, O’Dell C. R., T. H. Troland, van der Werf P. P.   +8 more
core   +3 more sources