Results 111 to 120 of about 1,415,660 (303)
Acta Crystallographica Section E, 2010 The title compound, C33H36N2O8, is the first example of a disubstituted peptidic pentacycloundecane (PCU) diol. The structure displays an array of inter- and intramolecular hydrogen bonding by both amide and alcohol functional groups.
Glenn E. M. Maguire +4 more
doaj +1 more source
Zinc(ii) coordination polymers with pseudopeptidic ligands [PDF]
, 2011 08.10.12 KB. Ok to add accepted version to Spiral., embargo elapsed (Sept 2012)Two new phenyl-bridged pseudopeptidic ligands have been prepared and structurally characterised.
Luis, SV +14 more
core +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Molecules, 2016 The purpose of this study is to confirm the impact of polar functional groups on inter and intra-molecular hydrogen bonding in haloperidol (HP) and droperidol (DP) and, hence, their effects on dissolution using a new approach.
Hardeep Saluja +3 more
doaj +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
Hydrogen Bonding in 2,2,2-Trifluoroethanol
Journal of Molecular ModelingAbstract Context 2,2,2-Trifluoroethanol (TFE) is known as a membrane mimetic solvent. The IR spectrum, 1H NMR spectrum and 13C NMR spin‒lattice relaxation times (T1) and nuclear Overhauser effect (NOE) data are consistent with extensive hydrogen bonding in TFE, but do not lead to structural features of the hydrogen bonding.
Soon, Ng +2 more
openaire +2 more sources
The use of molecular electrostatic potentials as hydrogen-bonding-donor parameters for QSAR studies
, 2004 Hydrogen bonding is an important interaction, which controls solubility, partitioning and transport of drugs and is an important force in drug-receptor interactions.
John C Dearden (16236848) +1 more
core +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source