Results 61 to 70 of about 1,512,277 (335)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
, 2019 The dominating trend of variable renewable energy sources (RES) continues to underpin the early retirement of baseload power generating sources such as coal, nuclear, and natural gas steam generators; however, the need to maintain system reliability remains the challenge.
openaire +4 more sources
A novel hybrid architecture for agriculture and land use in an integrated modeling framework : MATISSE (Methods and Tools for Integrated Sustainability Assesment) [PDF]
, 2008 As part of a cluster workshop on sustainability of hydrogen transport technologies held in Frankfurt on 21st February 2006, MATISSE researchers conducted break-out discussion groups with, and distributed self-completion questionnaires to, stakeholders in
Cassen, Christophe +4 more
core
Energy level displacement of excited np states of kaonic hydrogen
, 2005 We compute the energy level displacement of the excited np states of kaonic hydrogen within the quantum field theoretic and relativistic covariant model of strong low-energy bar-KN interactions suggested in EPJA21, 11 (2004).
A. N. Ivanov +22 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Production of atomic hydrogen by cosmic rays in dark clouds [PDF]
, 2018 The presence of small amounts of atomic hydrogen, detected as absorption dips in the 21 cm line spectrum, is a well-known characteristic of dark clouds.
Caselli, Paola +4 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Communications EngineeringAlkaline water electrolysers are ideal for gigawatt-scale hydrogen production due to the usage of non-precious metal and low-cost raw materials. However, their performances are modest with the separated electrode and diaphragm structure which can date ...
Zhuang Xu +7 more
doaj +1 more source
Some harvesting system transforming energy wastes of compressed air to electricity
E3S Web of Conferences, 2017 Energy harvesting devices are self-powered systems which are associated with input ambient energy and convert such energy to electrical one. In this study, we focus on input ambient energy deriving from compressed air.
Leszczynski Jacek S. +9 more
doaj +1 more source
Comprehensive rate coefficients for electron collision induced transitions in hydrogen
, 2013 Energy-changing electron-hydrogen atom collisions are crucial to regulating the energy balance in astrophysical and laboratory plasmas and relevant to the formation of stellar atmospheres, recombination in H-II clouds, primordial recombination, three ...
Onofrio, Roberto +2 more
core +1 more source