Results 51 to 60 of about 3,525,801 (303)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Hydrogen evolution on Pd modified CoCuZn and CoMnZn cathodes
Hydrogen evolution reaction (HER) was studied on four types of alkaline leached cathodes (CoCuZn/C, CoCuZn-Pd/C, CoMnZn/C and CoMnZn-Pd/C) in 1 M KOH solution at 25 degrees C.
Döner, Ali
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Summary: Conjugated polymers are emerging as promising organic photocatalysts for hydrogen evolution from water. However, it is still very challenging for conjugated polymers to realize highly efficient photocatalytic hydrogen evolution.
Zhicheng Hu +6 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
SHAPE DEPENDENT ELECTROCATALYTIC HYDROGEN EVOLUTION BY COPPER-ANTIMONY SULFIDE
BAU; et al.; INOGEN; Republic of Turkey, Ministry of Energy and Natural Resources; TENMARK; Turkish Airlines23rd World Hydrogen Energy Conference: Bridging Continents by H2, WHEC 2022 -- 26 June 2022 through 30 June 2022 -- Istanbul -- 186176The ...
Aslan, Emre +2 more
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Nickel thin films with different morphologies were prepared by electrodeposition from solutions with different additives. It is found by observing the nickel film morphology with SEM that the compact nickel films were prepared from solutions containing ...
Xiongxi Wu, Qifeng Gao, Zesong Li
doaj +1 more source
Attempts to develop hydrogen evolution photocatalysts usually result in low efficiency. Here the authors report a photocatalyst system by integrated interfacial design of stable covalent organic frameworks for high performance hydrogen evolution.
Ting He +13 more
doaj +1 more source

