Results 51 to 60 of about 634,511 (275)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Enhancement of bisphenol a removal from wastewater via the covalent functionalization of graphene oxide with short amine molecules

Case Studies in Chemical and Environmental Engineering, 2022
Water pollution is a serious environmental problem worldwide. This problem is augmented by the shortages in fresh water supplies in several parts of the world. Thus, the effective treatment and reuse of polluted water is an inevitable necessity.
Ali A.Q. Al-Qadri, Q.A. Drmosh, Sagheer A. Onaizi   +2 more
doaj   +1 more source

Electric Field Enhanced Hydrogen Storage on BN Sheet [PDF]

, 2009
Using density functional theory we show that an applied electric field substantially improves the hydrogen storage properties of a BN sheet by polarizing the hydrogen molecules as well as the substrate.
Bhatia, Chandrakumar, Grimme, J. Zhou, Lochan, Novoselov, P. Jena, Park, Q. Sun, Q. Wang, Sun, Sun, Sun, Sun, Wang, Watanabe, X. S. Chen, Yildirim, Yoon, Zhao   +19 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Ultrafast Hydrogen Production via Hydrolysis of MgH₂-NaH Composite

Metals
Magnesium hydride (MgH2) has attracted considerable interest due to a number of favourable characteristics for hydrogen production via hydrolysis. In this study, MgH2-NaH composites with varying composition ratios were prepared by ball milling for ...
Zhao Zhang, Zhenji Li, Wei Zhao, Yushan Zhang, Chong Peng, Changcheng Liu, Li Guo   +6 more
doaj   +1 more source

Synthesis and Performance of MOF-Based Non-Noble Metal Catalysts for the Oxygen Reduction Reaction in Proton-Exchange Membrane Fuel Cells: A Review

Nanomaterials, 2020
Hydrogen is widely regarded as a prime energy carrier for bridging the gap between renewable energy supply and demand. As the energy-generating component of the hydrogen cycle, affordable and reliable fuel cells are of key importance to the growth of the
Nicolas Delaporte, Etienne Rivard, Sadesh K. Natarajan, Pierre Benard, Michel L. Trudeau, Karim Zaghib   +5 more
doaj   +1 more source

Titanium-capped carbon chains as promising new hydrogen storage media

, 2010
The capacity of Ti-capped sp carbon atomic chains for use as hydrogen storage media is studied using first-principles density functional theory. The Ti atom is strongly attached at one end of the carbon chains via d-p hybridization, forming stable TiCn ...
Bogana, Börrnert, Chun-Sheng Liu, Crabtree, Dag, Delley, Durgun, Durgun, Henkelman, Hui An, Jin, Kim, Kubas, Lang, Largo, Lee, Liu, Perdew, Ravagnan, Ravagnan, Ravagnan, Roth, Sun, Sun, Wang, Yildirim, Yoon, Zhao, Zhi Zeng   +28 more
core   +1 more source