Results 61 to 70 of about 636,938 (293)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Coordinated Optimization of Intelligent Soft Open Points and Multiple Types of Shared Energy Storage in Distribution Networks Considering Flexibility Deficiency Risk

发电技术
ObjectivesTo address the operational security issues in the new-type distribution network caused by the high-penetration integration of renewable energy, this paper proposes a coordinated optimization method for intelligent soft open points and multiple ...
WANG Jie, XU Lijun, LI Xiaozhu, FAN Xiaochao, GULIZHATI∙Hailati, WANG Weiqing   +5 more
doaj   +1 more source

Cathode Supported Hybrid Direct Carbon Fuel Cells with Different Anodes

International Journal of Electrochemical Science, 2020
Three different types of hybrid direct carbon fuel cells were investigated for direct electrochemical oxidation of carbon black. One where anode-supported with a Ni/YSZ (yttria stabilized zirconia) anode and two cathode supported cells with either a NI ...
K. Kammer Hansen, V. Gil, L. Deleebeeck
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Turbopump thermodynamic cooling [PDF]

, 1972
System for cooling turbopumps used in cryogenic fluid storage facilities is described. Technique uses thermodynamic propellant vent to intercept pump heat at desired conditions.
Mckee, H. B., Patten, T. C.
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Titanium-capped carbon chains as promising new hydrogen storage media

, 2010
The capacity of Ti-capped sp carbon atomic chains for use as hydrogen storage media is studied using first-principles density functional theory. The Ti atom is strongly attached at one end of the carbon chains via d-p hybridization, forming stable TiCn ...
Bogana, Börrnert, Chun-Sheng Liu, Crabtree, Dag, Delley, Durgun, Durgun, Henkelman, Hui An, Jin, Kim, Kubas, Lang, Largo, Lee, Liu, Perdew, Ravagnan, Ravagnan, Ravagnan, Roth, Sun, Sun, Wang, Yildirim, Yoon, Zhao, Zhi Zeng   +28 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Dual-frequency ultrasonic-assisted enzymolysis for synthesis of microstructure regulated biomass-derived porous carbon for high-performance supercapacitors

Ultrasonics Sonochemistry
Biomass-derived porous carbon (PC) has emerged as a promising candidate for electrode materials in energy storage applications, effective pretreatment of the precursor is a key strategy for enhancing the electrochemical performance of PC.
Zhaocai Teng, Kuihua Han, Meimei Wang, Jianhui Qi, Jiangwei Liu, Yingjie Li   +5 more
doaj   +1 more source

Large diameter metal ring seal prevents gas leakage at 5000 psi [PDF]

, 1966
Large metal ring seal prevents gas leakage in hydrogen, helium, or nitrogen storage bottles at pressures up to 5,000 psi. The grooved ring seal which contains elastomer O-rings is installed between the mating faces of the access cover and the storage ...
Middelkoop, J. H.
core   +1 more source