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Hydrogen sulfide in hypertension
Current Opinion in Nephrology and Hypertension, 2016Hypertension is an important determinant of cardiovascular disease, and strict blood pressure regulation is beneficially associated with the risk for cardiovascular events or all-cause mortality. However, intensive antihypertensive treatment is not always sufficient to reach normotension.
van Goor, Harry +3 more
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Toxicology of Hydrogen Sulfide
Annual Review of Pharmacology and Toxicology, 1992Significant progress has been made in determining the action of sulfide on the primary target organs. It is reasonably clear that sulfide causes both K(+)-channel-mediated hyperpolarization of neurons and potentiation of other inhibitory mechanisms. It is not clear whether these processes are similar to those that occur in anoxia.
R J, Reiffenstein +2 more
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Hydrogen Sulfide and Neuroinflammation
2015The innate and adaptive immune system plays an important role in diverse forms of central nervous system (CNS) pathologies including neurodegenerative diseases and peripheral nerve injury. Evidence for an innate inflammatory response in Alzheimer's disease (AD) was described 20 years ago, and subsequent studies have documented roles of inflammation in ...
Kotaro, Kida, Fumito, Ichinose
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[Advances in hydrogen sulfide and hydrogen sulfide-releasing drugs].
Yao xue xue bao = Acta pharmaceutica Sinica, 2018Hydrogen sulfide (H(2)S) is considered as a new member of gasotransmitter family, following nitric oxide (NO) and carbon monoxide (CO). H2S exerts important biological effects in mammals, which has drawn more and more attention in recent years. It is proved that H(2)S has a role in the regulation of physiological and pathophysiological processes in the
Xiao-li, Wang +4 more
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