Results 41 to 50 of about 97,939 (280)

D-Cysteine Activates Chaperone-Mediated Autophagy in Cerebellar Purkinje Cells via the Generation of Hydrogen Sulfide and Nrf2 Activation

open access: yesCells, 2022
Chaperone-mediated autophagy (CMA) is a pathway in the autophagy-lysosome protein degradation system. CMA impairment has been implicated to play a role in spinocerebellar ataxia (SCA) pathogenesis. D-cysteine is metabolized by D-amino acid oxidase (DAO),
Erika Ueda   +6 more
doaj   +1 more source

Durable Physically Mixed Microporous and Mesoporous MOFs/Nanofiber Aerogel 3D Composites for Effective Toxic Gas Capture and Organophosphonate Detoxification

open access: yesAdvanced Functional Materials, EarlyView.
Ultralight 3D nanofibrous aerogels embedded with metal‐organic frameworks effectively capture and neutralize toxic gases and organophosphonates. Incorporating mesoporous UiO‐66‐NH2 and HKUST‐1 into PAN/PVP fibers enables high MOF loading while maintaining mechanical strength and structural stability.
Mai O. Abdelmigeed   +6 more
wiley   +1 more source

Study on the factors of hydrogen sulfide production from lignite bacterial sulfate reduction based on response surface method

open access: yesScientific Reports, 2023
Bacterial sulfate reduction (BSR) is one of the key factors leading to the anomalous accumulation of hydrogen sulphide in coal mines. Environmental factors such as temperature and pH play a crucial role in the metabolism and degradation of coal by ...
Qigen Deng   +5 more
doaj   +1 more source

Tracking the Dynamic and Interactive Metal Oxidation Changes in CoFe, CoNi, and NiFe Bimetallic Hydroxides for Electrocatalytic Oxygen Evolution

open access: yesAdvanced Functional Materials, EarlyView.
Operando hard X‐ray absorption spectroscopy is applied to track the dynamic and interactive metal oxidation changes in iron group bimetallic hydroxides under different chemical and electrochemical conditions. It shows that Co and Fe oxidation are relatively equal and synchronized in CoFeOxHy.
Jinzhen Huang   +6 more
wiley   +1 more source

An In Situ Study of the Topochemical Transformation of Hybrid Layered Hydroxides Into Metallic Nanocomposites

open access: yesAdvanced Functional Materials, EarlyView.
Herein, the topochemical transformation of cobalt‐based layered hydroxides into nanocomposites is investigated using advanced real‐time characterization techniques combined with thermogravimetric analysis. The study reveals how interlayer carboxylic acids direct the transformation pathway, highlighting the role of carbon content and anion length. These
Camilo Jaramillo‐Hernández   +5 more
wiley   +1 more source

Hydrogen sulfide improves diabetic kidney disease by reducing apoptosis of renal tubular epithelial cells

open access: yesLinchuang shenzangbing zazhi, 2020
Objective To investigate whether GYY4137, a sustained-release agent of hydrogen sulfide, plays a protective role in diabetic kidney disease and its possible mechanism.Methods C57 BL/6 J mice were injected with STZ(50 mg/kg×4 d) intraperitoneally and high-
YU Yan-ting   +5 more
doaj  

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Solvent‐Free Bonding Mechanisms and Microstructure Engineering in Dry Electrode Technology for Lithium‐Ion Batteries

open access: yesAdvanced Functional Materials, EarlyView.
Dry electrode technology revolutionizes battery manufacturing by eliminating toxic solvents and energy‐intensive drying. This work details two promising techniques: dry spray deposition and polymer fibrillation. How their unique solvent‐free bonding mechanisms create uniform microstructures for thicker, denser electrodes, boosting energy density and ...
Yuhao Liang   +7 more
wiley   +1 more source

H2S-Induced Sulfhydration: Biological Function and Detection Methodology

open access: yesFrontiers in Pharmacology, 2017
At appropriate concentrations, hydrogen sulfide, a well-known gasotransmitter, plays important roles in both physiology and pathophysiology. Increasing evidence suggests that modifying thiol groups of specific cysteines in target proteins via ...
Da Zhang   +6 more
doaj   +1 more source

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