Results 91 to 100 of about 23,079 (207)

Aminomethylation/hydrogenolysis as an alternative to direct methylation of metalated isoquinolines – a novel total synthesis of the alkaloid 7-hydroxy-6-methoxy-1-methylisoquinoline

open access: yesBeilstein Journal of Organic Chemistry, 2018
Highly-substituted isoquinolines are important scaffolds in syntheses of natural products and in drug development and hence, effective synthetic approaches are required.
Benedikt C. Melzer   +2 more
doaj   +1 more source

Development of a Self‐Adjuvanting Influenza Peptide–Glycolipid Conjugate Inducing CD8+ T‐Cell Immunity

open access: yesChemBioChem, Volume 27, Issue 5, 13 March 2026.
The glycolipid‐peptide antigen complexes for self‐adjuvanting conjugates were successfully synthesized, and, with the HLA‐transgenic mice, the antigen‐specific CD8+ T cell expansion was exhibited. The results provide useful insights for the design and synthesis of vaccine conjugates using glycolipid antigen as an adjuvant.
Shunya Kikuchi   +4 more
wiley   +1 more source

Synthesis of rigid p-terphenyl-linked carbohydrate mimetics

open access: yesBeilstein Journal of Organic Chemistry, 2014
An approach to β-D-2-aminotalose- and β-D-2-aminoidose-configured carbohydrate mimetics bearing a phenyl substituent is described. Unnatural divalent rigid p-terphenyl-linked C-aryl glycosides with 2.0 nm dimension are available using Suzuki cross ...
Maja Kandziora, Hans-Ulrich Reissig
doaj   +1 more source

Liquid‐Phase Syngas‐To‐Methanol at Low Temperature: Mixed Alcohol Solvent‐Controlled Pathways for Circular Carbon Manufacturing

open access: yesChemSusChem, Volume 19, Issue 5, 13 March 2026.
Low‐temperature liquid‐phase methanol synthesis from syngas was demonstrated over CuO/ZnO/Al2O3 catalysts using mixed alcohol solvents. Solvent composition controls ester intermediate and methanol productivity. Methanol is a primary platform chemical for circular manufacturing.
Guanfu Liu   +5 more
wiley   +1 more source

Improving Purity Propylene Glycol by Modifying Glycerol Hydrogenolysis Process

open access: yesJournal of Chemical Engineering Research Progress
The chemical industry in Indonesia continues to grow in terms of innovation and technology. One field that has experienced a significant increase is supporting materials, such as propylene glycol.
Alfina Rahmatul Azizah   +4 more
doaj   +1 more source

Effect of Preparation Method on Catalytic Activity of Ni/ γ-Al2O3 Catalysts

open access: yesIngeniería, 2017
The performance of catalysts has been shown to be strongly dependent on their methods of preparation.  A study to examine the relationship between catalyst preparation procedures and the structure, dispersion, activity, and selectivity of the finished ...
Bárbara Cristina Miranda Morales
doaj   +1 more source

Glycosylation efficiencies on different solid supports using a hydrogenolysis-labile linker

open access: yesBeilstein Journal of Organic Chemistry, 2013
Automated oligosaccharide assembly requires suitable linkers to connect the first monosaccharide to a solid support. A new hydrogenolysis-labile linker that is stable under both acidic and basic conditions was designed, synthesized and coupled to ...
Mayeul Collot   +3 more
doaj   +1 more source

Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model. [PDF]

open access: yes, 2013
The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di-
Garg, Neil K, Goetz, Adam E
core  

Stereoselective Synthesis of Optically Active Aspartic Acid from Derivatives of Fumaric Acid and Maleic Acid [PDF]

open access: yes
Stereoselective synthesis of optically active aspartic acid from derivatives of fumaric acid and maleic ...
Harada, K., Matsumoto, K.
core   +1 more source

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