Results 91 to 100 of about 151,408 (235)

Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase

open access: yesACS Medicinal Chemistry Letters, 2019
Multitarget anti-inflammatory drugs interfering with the arachidonic acid cascade exhibit superior efficacy. In this study, a prototype dual inhibitor of soluble epoxide hydrolase (sEH) and LTA4 hydrolase (LTA4H) with submicromolar activity toward both targets has been designed and synthesized.
Kerstin Hiesinger   +10 more
openaire   +4 more sources

Glycoside hydrolase gene transcription by Alicyclobacillus acidocaldarius during growth on wheat arabinoxylan and monosaccharides: a proposed xylan hydrolysis mechanism

open access: yesBiotechnology for Biofuels, 2018
Background Metabolism of carbon bound in wheat arabinoxylan (WAX) polysaccharides by bacteria requires a number of glycoside hydrolases active toward different bonds between sugars and other molecules.
Brady D. Lee   +3 more
doaj   +1 more source

The plant Nudix hydrolase family. [PDF]

open access: yes, 2008
Nudix hydrolases are a family of proteins defined by a conserved amino-acid sequence GX(5)-EX(7)REUXEEXGU, where U is a hydrophobic residue. These enzymes are widely distributed among all classes of organisms and catalyze, with varying degrees of ...
Kraszewska, Elzbieta
core  

Engineering of Bioenergy Crops: Dominant Genetic Approaches to Improve Polysaccharide Properties and Composition in Biomass. [PDF]

open access: yes, 2020
Large-scale, sustainable production of lignocellulosic bioenergy from biomass will depend on a variety of dedicated bioenergy crops. Despite their great genetic diversity, prospective bioenergy crops share many similarities in the polysaccharide ...
Brandon, Andrew G, Scheller, Henrik V
core  

State of enzyme systems of polymorphonuclear leukocytes by the gingival margin level correction

open access: yesКубанский научный медицинский вестник, 2015
The paper deals with the results of cytochemical studies of biologically active enzyme systems of neutrophilic granulocytes and their comparative analysis to assess the effectiveness of gingiva preparation and scalpel use for the correction of the ...
M. V. Goman   +2 more
doaj  

Polymer degrading marine Microbulbifer bacteria: an un(der)utilized source of chemical and biocatalytic novelty

open access: yesBeilstein Journal of Organic Chemistry
Microbulbifer is a genus of halophilic bacteria that are commonly detected in the commensal marine microbiomes. These bacteria have been recognized for their ability to degrade polysaccharides and other polymeric materials.
Weimao Zhong, Vinayak Agarwal
doaj   +1 more source

A chemical biology approach to control endocannabinoid biosynthesis [PDF]

open access: yes, 2015
Endocannabinoids play an essential role in human health and disease, regulating processes such as immunomodulation, energy balance and neurotransmission.
Van der Selt, Marcelis
core  

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