Results 241 to 250 of about 135,084 (297)
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Current Opinion in Chemical Biology, 2000
A number of nitrile-related enzymes have been screened over the past year for use in synthetic applications. There have also been significant advances in our understanding of the structures and modes of regulation of metal-containing nitrile hydratases.
M, Kobayashi, S, Shimizu
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A number of nitrile-related enzymes have been screened over the past year for use in synthetic applications. There have also been significant advances in our understanding of the structures and modes of regulation of metal-containing nitrile hydratases.
M, Kobayashi, S, Shimizu
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Prostaglandins & Other Lipid Mediators, 2002
The leukotrienes (LTs) are a family of lipid mediators involved in inflammation and allergy. Leukotriene B4 is a classical chemoattractant, which triggers adherence and aggregation of leukocytes to the endothelium at only nanomolar concentrations.
Jesper Z, Haeggström +4 more
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The leukotrienes (LTs) are a family of lipid mediators involved in inflammation and allergy. Leukotriene B4 is a classical chemoattractant, which triggers adherence and aggregation of leukocytes to the endothelium at only nanomolar concentrations.
Jesper Z, Haeggström +4 more
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ADP-ribosylarginine hydrolases
Molecular and Cellular Biochemistry, 1994ADP-ribosylation is a reversible post-translational modification of proteins involving the addition of the ADP-ribose moiety of NAD to an acceptor protein or amino acid. NAD:arginine ADP-ribosyltransferase, purified from numerous animal tissues, catalyzes the transfer of ADP-ribose to an arginine residue in proteins.
T, Takada, I J, Okazaki, J, Moss
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Prostaglandins & Other Lipid Mediators, 2002
Endocannabinoids (endogenous ligands of cannabinoid receptors) such as anandamide (N-arachidonoylethanolamine) and 2-arachidonoylglycerol (2-AG) are inactivated upon enzymatic hydrolysis. Recent progress in the enzymological and molecular biological studies on the 'endocannabinoid hydrolases' is reviewed in this article.
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Endocannabinoids (endogenous ligands of cannabinoid receptors) such as anandamide (N-arachidonoylethanolamine) and 2-arachidonoylglycerol (2-AG) are inactivated upon enzymatic hydrolysis. Recent progress in the enzymological and molecular biological studies on the 'endocannabinoid hydrolases' is reviewed in this article.
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Chemico-Biological Interactions, 1988
Epoxide hydrolase activity is recovered in the high-speed supernatant fraction from the liver of all mammals so far examined, including man. For some as yet unexplained reason, the rat has a very low level of this activity, so that cytosolic epoxide hydrolase is generally studied in mice.
J, Meijer, J W, DePierre
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Epoxide hydrolase activity is recovered in the high-speed supernatant fraction from the liver of all mammals so far examined, including man. For some as yet unexplained reason, the rat has a very low level of this activity, so that cytosolic epoxide hydrolase is generally studied in mice.
J, Meijer, J W, DePierre
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Leukotriene A4 hydrolase: An epoxide hydrolase with peptidase activity
Biochemical and Biophysical Research Communications, 1990Purified leukotriene A4 hydrolase from human leukocytes is shown to exhibit peptidase activity towards the synthetic substrates alanine-4-nitroanilide and leucine-4-nitroanilide. The enzymatic activity is abolished after heat treatment (70 degrees C, 30 min).
J Z, Haeggström +3 more
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Lysosomal hydrolases of the epidermis.
British Journal of Dermatology, 1975Four distinct peptide hydrolases (EC 3-4) have been characterized in guinea-pig epidermis; these are cathepsin B1, cathepsin C, cathepsin D and arylamidase. Their properties are consistent with those of lysosomal enzymes. Cathepsin E was not detected.
P D, Mier, J J, van den Hurk
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Endo-Xylogalacturonan Hydrolase
2003Commercial pectinases used in apple juice manufacturing contain a mixture of pectin-degrading enzyme activities. Nevertheless, fragments of branched pectic molecules (or pectic hairy regions) are resistant to degradation, and can cause membrane fouling in the final ultrafiltration step of concentrated apple juice.
Herweijer, M.A. +6 more
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