Results 41 to 50 of about 520,734 (241)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Interaction Between Two Rigid Hydrophobic Spheres Oscillating in an Infinite Brinkman–Stokes Fluid
MathematicsThis study investigates the dynamics of two oscillating rigid spheres moving through an infinite porous medium saturated with Stokes fluid flow, addressing the problem of how fluid properties, permeability, frequency, and slip length influence the system.
Azza M. Algatheem +2 more
doaj +1 more source
Ecology of Nontuberculous Mycobacteria
Microorganisms, 2021 Nontuberculous mycobacteria (NTM) are opportunistic human pathogens that are widespread in the human environment. In fact, NTM surround humans. The basis for their widespread presence in soils and natural and human-engineered waters lies primarily in ...
Joseph O. Falkinham
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
PharmaceuticsIntroduction: In this study, we aimed to optimize the microfluidizer-based preparation of poly(lactic-co-glycolic acid) nano-micelles (PLGANM), increasingly used for parenteral delivery of poorly water-soluble drugs but typically exhibiting poor physical
Esma Nur Develi Arslanhan +4 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Deposition of transparent, hydrophobic polydimethylsiloxane - nanocrystalline TiO2 hybrid films on glass substrate [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2010 Transparent, hydrophobic hybrid films were deposited on glass substrate from solution containing hydroxyl-terminatedpolydimethylsiloxane (PDMS) and TiO2 sol by using a dip coating method.
On-uma Nimittrakoolchai +1 more
doaj
Jurnal Teknik Kimia dan Lingkungan, 2023 Proses pengolahan minyak di Indonesia sangat menguntungkan untuk perekonomian negara. Tetapi disamping itu, terdapat hal yang meyebabkan kerugian yaitu terjadinya tumpahan minyak.
Bramantya Bramantya +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source