Results 51 to 60 of about 139,061 (296)

The His-tag as a decoy modulating preferred orientation in cryoEM

open access: yesFrontiers in Molecular Biosciences, 2022
The His-tag is a widely used affinity tag that facilitates purification by means of affinity chromatography of recombinant proteins for functional and structural studies.
Raquel Bromberg   +13 more
doaj   +1 more source

Designing new thermoreversible gels by molecular tailoring of hydrophilic-hydrophobic interactions

open access: yes, 2000
We have shown that the lattice fluid hydrogen bond (LFHB) model can successfully quantify the first-order volume transition in hydrogels. The model predicts that a critical balance of hydrophilic and hydrophobic interactions is required for a gel to ...
S. Varghese   +5 more
core   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysis

open access: yesFood Chemistry: X
Various lipid and biopolymer-based nanocarriers have been developed to encapsulate food ingredients. The selection of nanocarrier type, preparation techniques, and loading methods should consider the compatibility of nutrient properties, nanocarrier ...
Ruihan Huang   +3 more
doaj   +1 more source

Separation of highly hydrophilic nicotinamide metabolites using a COSMOSIL PBr column

open access: yesMethodsX, 2023
Highly hydrophilic compounds such as nicotinamide metabolites are very difficult to separate via high-performance liquid chromatography (HPLC) using octadecyl (C18) columns. In general, for the separation of hydrophilic compounds, hydrophilic interaction
Makoto Ozaki   +2 more
doaj   +1 more source

Developing a General Interaction Potential for Hydrophobic and Hydrophilic Interactions

open access: yes, 2016
We review direct force measurements on a broad class of hydrophobic and hydrophilic surfaces. These measurements have enabled the development of a general interaction potential per unit area, W(D) = −2γiHy exp­(−D/DH) in terms of a nondimensional Hydra ...
Michael V. Rapp (1650238)   +9 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Changing Water Affinity from Hydrophobic to Hydrophilic in Hydrophobic Channels

open access: yes, 2016
The behavior of water at hydrophobic interfaces can play a significant role in determining chemical reaction outcomes and physical properties. Carbon nanotubes and aluminophosphate materials have one-dimensional hydrophobic channels, which are entirely ...
Kenji Hata (1294497)   +3 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Experimental Study on Van der Waals Interactions Between Organic Groups of Quaternary Ammonium Salt Surfactants and Montmorillonite in Aqueous Solutions

open access: yesInorganics
Obtaining the dielectric constant and refractive index of the siloxane surface of montmorillonite (Mnt) and organic groups is difficult, limiting the study of Van der Waals (VDW) interactions between the hydrophilic end of quaternary ammonium surfactants
Yongzheng Fu   +6 more
doaj   +1 more source

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