Results 81 to 90 of about 755,747 (299)

RAFT polymers for protein recognition

Beilstein Journal of Organic Chemistry, 2010
A new family of linear polymers with pronounced affinity for arginine- and lysine-rich proteins has been created. To this end, N-isopropylacrylamide (NIPAM) was copolymerized in water with a binding monomer and a hydrophobic comonomer using a living ...
Alan F. Tominey, Julia Liese, Sun Wei, Klaus Kowski, Thomas Schrader, Arno Kraft   +5 more
doaj   +1 more source

A natural based method for hydrophobic treatment of natural fiber material

Acta Chimica Slovenica, 2017
A treatment for hydrophobic functionalization of natural fiber materials is developed. This hydrophobic treatment is based mainly on natural products.
Thomas Kick, Thomas Grethe, Boris Mahltig   +2 more
doaj   +1 more source

Water structuring and collagen adsorption at hydrophilic and hydrophobic silicon surfaces

, 2009
The adsorption of a collagen fragment on both a hydrophobic, hydrogen-terminated and a hydrophilic, natively oxidised Si surface is investigated using all-atom molecular dynamics. While favourable direct protein-surface interactions via localised contact
Bacáková, Bujnowski, Cole, Colombi Ciacchi, Cormack, Daniel J. Cole, García, Grayson, Hal Davis, Horinek, et al., Hower, Jorgensen, Jönsson, Kabsch, Keller, Keselowsky, Kim, Latour, Lee, Lingenfelder, Liu, Lucio Colombi Ciacchi, Mike C. Payne, Montserret, Raffaini, Raffaini, Schröder, Service, Shen, Su, van Wachem, Vogler, Vogler, Voskerician, Wilson, Zangi   +35 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Hydrodynamics of the Developing Region in Hydrophobic Microchannels: A Dissipative Particle Dynamics Study

, 2012
Dissipative Particle Dynamics (DPD) is becoming a popular particle based method to study flow through microchannels due to the ease with which the presence of biological cells or DNA chains can be modeled.
Patnaik, B. S. V., Ranjith, S. Kumar, Vedantam, Srikanth   +2 more
core   +1 more source

Is it the shape of the cavity, or the shape of the water in the cavity? [PDF]

, 2013
Historical interpretations of the thermodynamics characterizing biomolecular recognition have marginalized the role of water. An important (even, perhaps, dominant) contribution to molecular recognition in water comes from the “hydrophobic effect,” in ...
Lockett, Matthew R., Moustakas, Demetri T., Snyder, Phillip W., Whitesides, George McClelland   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Drag force on a sphere moving towards an anisotropic super-hydrophobic plane

, 2011
We analyze theoretically a high-speed drainage of liquid films squeezed between a hydrophilic sphere and a textured super-hydrophobic plane, that contains trapped gas bubbles.
Asmolov, Evgeny S., Belyaev, Aleksey V., Vinogradova, Olga I.   +2 more
core   +1 more source

Intrusion and extrusion of water in hydrophobic nanopores [PDF]

, 2017
Heterogeneous systems composed of hydrophobic nanoporous materials and water are capable, depending on their characteristics, of efficiently dissipating (dampers) or storing ("molecular springs") energy.
Casciola, Carlo Massimo, Giacomello, Alberto, Grosu, Yaroslav, Tinti, Antonio   +3 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source