Results 151 to 160 of about 6,262 (261)

Insights from electromechanical simulations to assess omecamtiv mecarbil efficacy in heart failure

The Journal of Physiology, EarlyView.
Abstract figure legend Impact of Omecamtiv Mecarbil (OM) on in‐silico models of heart failure. A mathematical electromechanical model of human ventricular tissue is used to simulate the effects of OM in heart failure with reduced ejection fraction (HFrEF).
Maria Teresa Mora, Ilse van Herck, Cécile Daversin‐Catty, Henrik Finsberg, Jordi Llopis‐Lorente, Javier Saiz, Hermenegild Arevalo, Samuel Wall, Beatriz Trenor   +8 more
wiley   +1 more source

Modal response characterizations and mechanism separation modeling of amphibious vehicle body under different water entry depths. [PDF]

iScience
Li G, Bao K, Wang W, Zuo Z, Han Z, Zhao C, Wang H.   +6 more
europepmc   +1 more source

Hydrostatic Pressure Induces Osteogenic Differentiation of Single Stem Cells in 3D Viscoelastic Microgels. [PDF]

Small Sci
İyisan N, Rangel F, Funke L, Pan B, Özkale B.   +4 more
europepmc   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

A constitutive modelling framework for applications to in vivo longitudinal data: Evaluation in a 60‐day head‐down bed rest study on arterial function

The Journal of Physiology, EarlyView.
Abstract figure legend We proposed a computational constitutive modelling framework that leverages longitudinal acquisitions of haemodynamic waveforms at multiple arterial locations to achieve a biomechanical characterisation of their (micro)structural remodelling processes.
Alessandro Giudici, Karen Barchetti, Umit Gencer, Hakim Khettab, Elie Mousseaux, Carole Leguy, Tammo Delhaas, Rosa Maria Bruno, Bart Spronck, Pierre Boutouyrie   +9 more
wiley   +1 more source

Study on floor large deformation and failure mechanism of water-rich soft rock roadway. [PDF]

Sci Rep
Li L, Zhang Y, Zhou R, Qi K, Zhang Y, Li Q.   +5 more
europepmc   +1 more source

Gas exchange and pulmonary stress variations during SCUBA and breath‐hold diving in open seawater

The Journal of Physiology, EarlyView.
Abstract figure legend Healthy, trained divers were studied before, during and after diving in open seawater with different techniques. SCUBA divers (diving to 15 or 40 m with air; cycling at depth) and breath‐hold divers (BHDs; sled‐assisted dives to 15, 25 or 40 m) underwent underwater and surface arterial blood gas (ABG) sampling.
Matteo Paganini, Tommaso Antonio Giacon, Simona Mrakic‐Sposta, Luca Martani, Danilo Cialoni, Lorenzo Zucchi, Vincenzo Maffei, Rosario Cifali, Mariano Marmo, Enrico M Camporesi, Richard E Moon, Gerardo Bosco   +11 more
wiley   +1 more source

Advanced MMC-Based Hydrostatic Bearings for Enhanced Linear Motion in Ultraprecision and Micromachining Applications. [PDF]

Micromachines (Basel)
Khaghani A, Ivanov A, Mortazavi M.
europepmc   +1 more source

Mechanisms reducing parasympathetic activity in chronic hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Parasympathetic activity is reduced in chronic hypoxia, but the underlying mechanism(s) are unclear. Using β‐adrenergic blockade to isolate parasympathetic control of heart rate at sea level and after 9‐12 days at high altitude, we investigated whether (i) chemoreflex activation, (ii) increased pulmonary ventilation and/or (iii ...
Lauren E. Maier, Andrew Douglas, Katharine Foster, Elliott J. Jenkins, Liam D. Corr, Peter Rasmussen, James Anholm, Travis D. Gibbons, Phil N. Ainslie, Mike Stembridge, Christoph Siebenmann   +10 more
wiley   +1 more source

Inflammation induced by snake venoms optimizes envenomation

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustrating mechanisms underlying direct vascular absorption and subsequent movement of venom toxins into the tissues consequent to snakebite. A, snakebite into prey deposits venom toxins into the tissue interstitium, with the venom then causing acute inflammation primarily in venules.
Dirk F. van Helden, Neil Spratt, Peter J. Dosen, Sally A. McFadden, John Holdsworth, Daniel J Beard, Kirsten Coupland, Phillip Jobling, Todd A. Hardy, Derek R. Laver   +9 more
wiley   +1 more source