Results 1 to 10 of about 19,186 (210)
Next-Generation HDAC Inhibitors: Advancing Zinc-Binding Group Design for Enhanced Cancer Therapy [PDF]
CellsHistone deacetylases (HDACs) are pivotal epigenetic regulators that control gene expression, cell proliferation, and differentiation, and their dysregulation is closely associated with the onset and progression of multiple cancers.
Mohammed Hawash
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The hiuABC operon mediates xenosiderophore utilization in Caulobacter crescentus [PDF]
Journal of BacteriologyCaulobacter species are common residents of soil and aquatic ecosystems, where bioavailable iron is often extremely limited. Like other diderm bacteria, Caulobacter crescentus can acquire Fe(III) via outer-membrane TonB-dependent transporters (TBDTs ...
Sergio Hernandez-Ortiz +2 more
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Fimsbactin Siderophores From a South African Marine Sponge Symbiont, Marinomonas sp. PE14‐40 [PDF]
Microbial BiotechnologyLow iron levels in marine habitats necessitate the production of structurally diverse siderophores by many marine bacterial species for iron acquisition.
Nompumelelo Philile Praiseworth Ikegwuoha +7 more
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Evaluation of the effects of different hydroxamates and a sulfosuccinamate in the direct flotation of iron ore tailings [PDF]
REM: International Engineering Journal, 2023 Recent events involving iron ore tailings dam collapses have emphasized the need for developing alternative ways of depositing tailings. This study aims to evaluate the effects of using three hydroxamates and a sulfosuccinamate as collectors in the ...
Leonardo Júnior Fernandes Campos +1 more
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Biosynthesis Pathways, Transport Mechanisms and Biotechnological Applications of Fungal Siderophores
Journal of Fungi, 2021 Iron (Fe) is the fourth most abundant element on earth and represents an essential nutrient for life. As a fundamental mineral element for cell growth and development, iron is available for uptake as ferric ions, which are usually oxidized into complex ...
Lorenzo Pecoraro +8 more
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Journal of Fungi, 2023 Iron is a micronutrient required by almost all living organisms. Despite being essential, the availability of this metal is low in aerobic environments. Additionally, mammalian hosts evolved strategies to restrict iron from invading microorganisms.
Alexandre Melo Bailão +7 more
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SpoT Induces Intracellular Salmonella Virulence Programs in the Phagosome. [PDF]
, 2020 Guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), together named (p)ppGpp, regulate diverse aspects of Salmonella pathogenesis, including synthesis of nutrients, resistance to inflammatory mediators, and expression of secretion ...
Fitzsimmons, Liam F +8 more
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HDAC Inhibitors for the Therapy of Triple Negative Breast Cancer
Pharmaceuticals, 2022 Triple negative breast cancer (TNBC) is an urgent as well as huge medical challenge, which is associated with poor prognosis and responsiveness to chemotherapies.
Cristina Maccallini +5 more
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Open Agriculture, 2021 Microorganisms adopt a unique mechanism for sequestration and transport of bound iron by producing iron-chelating molecules called siderophores. Siderophores play an important role in colonization of microbes in iron-deficient sites of the host, hence ...
Kumar Gulshan +3 more
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Molecules, 2023 This work investigated the hydrophobic flocculation of cassiterite using four alkyl hydroxamic acids with varying carbon chain lengths, i.e., hexyl hydroxamate (C6), octyl hydroxamate (C8), decyl hydroxamate (C10) and dodecyl hydroxamate (C12), as ...
Saizhen Jin, Qing Shi, Leming Ou
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