Results 121 to 130 of about 19,186 (210)

Oligoglyceric acid synthesis by autocondensation of glyceroyl thioester [PDF]

The autocondensation of the glyceroyl thioester, S-glyceroyl-ethane-thiol, yielded olioglyceric acid. The rates of autocondensation and hydrolysis of the thioester increased from pH 6.5 to pH 7.5 in 2,6-lutidine and imidazole buffers.
Weber, A. L.
core   +1 more source

Genetically Tunable Enzymatic C‒H Amidation for Lactam Synthesis [PDF]

, 2019
A major challenge in carbon‒hydrogen (C‒H) bond functionalization is to have the catalyst control precisely where a reaction takes place. Here we report engineered cytochrome P450 enzymes that perform unprecedented enantioselective C‒H amidation ...
Arnold, Frances H., Cho, Inha, Jia, Zhi-Jun   +2 more
core  

Inhibitors of Bacterial \u3cem\u3eN\u3c/em\u3e-succinyl-L,L-diaminopimelic Acid Desuccinylase (DapE) and Demonstration of in vitro Antimicrobial Activity [PDF]

, 2009
The dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) is a critical bacterial enzyme for the construction of the bacterial cell wall. A screen biased toward compounds containing zinc-binding groups (ZBG’s) including thiols, carboxylic ...
Armoush, Nicola, Becker, Daniel P., Gillner, Danuta, Holz, Richard C.   +3 more
core   +1 more source

Hydroxamic Acid as Donors. Chromium (III) Complexes with Hydroxamic Acids

, 1971
Hydroxamic acid complexes, [Cr(RH)3]0 have been prepared and their structures assigned on the basis of molar conductance, magnetic and spectral measurements. Magnetic moments show three unpaired electrons per chromium for each complex. The complexes have two d-d transitions in the visible region.
openaire   +1 more source

Synthesis of β- and γ-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidates [PDF]

, 2008
Giessmann, Dirk, Haemers, Timothy, Hillaert, Ulrik, Jomaa, Hassan, Link, Andreas, Ortmann, Regina, Schlitzer, Martin, Van Calenbergh, Serge, Verbrugghen, Thomas, Wiesner, Jochen   +9 more
core   +1 more source

The chemical basis for the origin of the genetic code and the process of protein synthesis [PDF]

The principles upon which the process of protein synthesis and the genetic code were established are elucidated. Extensive work on nuclear magnetic resonance studies of both monomermonomer and monoamino acid polynucleotide interactions is included. A new

core   +1 more source

Rational design and synthesis of non-competitive transcription inhibitors targeting a conserved RNA polymerase-σ ^<i>A</i> interface. [PDF]

RSC Adv
Tandi M, Hati N, Kore M, Behera D, Patel T, Eeba, Agarwal N, Gopal B, Sundriyal S.   +8 more
europepmc   +1 more source

^44gSc from metal calcium targets for PET [PDF]

, 2012
Barnhart, T. E., Engle, J. W., Gagnon, K., Lewis, Jason S., Severin, Gregory, Valdovinos, H. F.   +5 more
core   +1 more source

Development of an inhibitory monoclonal nanobody targeting Streptococcus pyogenes siderophore binding protein FtsB. [PDF]

J Biol Chem
Fernandez-Perez J, de Vega S, Caaveiro JMM, Nakakido M, Nagatoishi S, Senoo A, Tanoi K, Nozawa T, Nakagawa I, Tsumoto K.   +9 more
europepmc   +1 more source

Mapping the nonribosomal specificity code through promiscuity-guided A-domain engineering. [PDF]

Chem Sci
Stanišić A, Svensson CM, Müll M, Bernal FA, Zeihe H, Ettelt U, Kries H.   +6 more
europepmc   +1 more source