Results 51 to 60 of about 21,152 (225)

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

SEPARATION AND PRECONCENTRATION OF COPPER (II) ION BY FATTY HYDROXAMIC ACIDS IMMOBILIZED ONTO AMBERLITE XAD – 4 RESIN

open access: yesIndonesian Journal of Chemistry, 2010
A method of copper (II) ion preconcentration and separation from other ions by using a column containing fatty hydroxamic acids - loaded Amberlite XAD 4 resin (FHA-Amb) is described.
Dedy Suhendra   +4 more
doaj   +1 more source

Hydroxamic acids interactions with metals in aqueous and micellar media: a mechanistic study of complexation reactions and metallacrown formation [PDF]

open access: yes, 2012
This thesis is focused on the different aspects of hydroxamic acids coordination, in particular on their ability to give rise to metal complexes of different stoichiometry and geometry.
BECCIA, MARIA ROSA
core   +1 more source

Hydrogel Embedding of Mesenchymal Stem Cells Supports Extracellular Vesicle Production

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 4, Page 939-949, April 2026.
This study investigates the effects of 3D culture conditions on extracellular vesicle (EV) production by mesenchymal stem cells (MSCs) in a gelatin‐based hydrogel matrix (GelMA). The EVs from both conditions were found to have similar morphological, molecular, and functional properties, but 3D cultures produced more total EVs per volume.
Rachel K. Moen   +5 more
wiley   +1 more source

Preparation of Aliphatic Hydroxamic Acid from Litsea cubeba Kernel Oil and Its Application to Flotation of Fe(III)-Activated Wolframite

open access: yesMolecules, 2023
Litsea cubeba is a characteristic woody oil resource in Hunan. As a solid waste of woody oil resources, Litsea cubeba kernels are rich in Litsea cubeba kernel oil with a carbon chain length of C10–12 fatty acid.
Jingjing Xiao   +6 more
doaj   +1 more source

A minimalist chemical model of matrix metalloproteinases- Can small peptides mimic the more rigid metal binding sites of proteins? [PDF]

open access: yes, 2013
In order to develop a minimalist chemical model of matrix metalloproteinases (MMPs), we synthesized a pentadecapeptide (Ac-KAHEFGHSLGLDHSK-NH2) corresponding to the catalytic zinc(II) binding site of human MMP-13.
Aguilar   +48 more
core   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang   +18 more
wiley   +1 more source

Examining the PM6 semiempirical method for pKa prediction across a wide range of oxyacids [PDF]

open access: yes, 2009
The pK~a~ estimation ability of the semiempirical PM6 method was evaluated across a broad range of oxyacids and compared to results obtained using the SPARC software program.
Kaya Forest   +2 more
core   +1 more source

Field-effect transistors assembled from functionalized carbon nanotubes

open access: yes, 2006
We have fabricated field effect transistors from carbon nanotubes using a novel selective placement scheme. We use carbon nanotubes that are covalently bound to molecules containing hydroxamic acid functionality.
Appenzeller J.   +41 more
core   +1 more source

Computational study of radicals derived from hydroxyurea and its methylated analogues. [PDF]

open access: yes, 2012
Structural and electronic properties and chemical fate of free radicals generated from hydroxyurea (HU) and its methylated analogues N-methylhydroxyurea (NMHU) and O-methylhydroxyurea (OMHU) are of utmost importance for their biological and ...
Birus, Mladen   +4 more
core   +1 more source

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