Results 51 to 60 of about 21,152 (225)
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
A method of copper (II) ion preconcentration and separation from other ions by using a column containing fatty hydroxamic acids - loaded Amberlite XAD 4 resin (FHA-Amb) is described.
Dedy Suhendra +4 more
doaj +1 more source
Hydroxamic acids interactions with metals in aqueous and micellar media: a mechanistic study of complexation reactions and metallacrown formation [PDF]
This thesis is focused on the different aspects of hydroxamic acids coordination, in particular on their ability to give rise to metal complexes of different stoichiometry and geometry.
BECCIA, MARIA ROSA
core +1 more source
Hydrogel Embedding of Mesenchymal Stem Cells Supports Extracellular Vesicle Production
This study investigates the effects of 3D culture conditions on extracellular vesicle (EV) production by mesenchymal stem cells (MSCs) in a gelatin‐based hydrogel matrix (GelMA). The EVs from both conditions were found to have similar morphological, molecular, and functional properties, but 3D cultures produced more total EVs per volume.
Rachel K. Moen +5 more
wiley +1 more source
Litsea cubeba is a characteristic woody oil resource in Hunan. As a solid waste of woody oil resources, Litsea cubeba kernels are rich in Litsea cubeba kernel oil with a carbon chain length of C10–12 fatty acid.
Jingjing Xiao +6 more
doaj +1 more source
A minimalist chemical model of matrix metalloproteinases- Can small peptides mimic the more rigid metal binding sites of proteins? [PDF]
In order to develop a minimalist chemical model of matrix metalloproteinases (MMPs), we synthesized a pentadecapeptide (Ac-KAHEFGHSLGLDHSK-NH2) corresponding to the catalytic zinc(II) binding site of human MMP-13.
Aguilar +48 more
core +1 more source
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source
Examining the PM6 semiempirical method for pKa prediction across a wide range of oxyacids [PDF]
The pK~a~ estimation ability of the semiempirical PM6 method was evaluated across a broad range of oxyacids and compared to results obtained using the SPARC software program.
Kaya Forest +2 more
core +1 more source
Field-effect transistors assembled from functionalized carbon nanotubes
We have fabricated field effect transistors from carbon nanotubes using a novel selective placement scheme. We use carbon nanotubes that are covalently bound to molecules containing hydroxamic acid functionality.
Appenzeller J. +41 more
core +1 more source
Computational study of radicals derived from hydroxyurea and its methylated analogues. [PDF]
Structural and electronic properties and chemical fate of free radicals generated from hydroxyurea (HU) and its methylated analogues N-methylhydroxyurea (NMHU) and O-methylhydroxyurea (OMHU) are of utmost importance for their biological and ...
Birus, Mladen +4 more
core +1 more source

