We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel +16 more
wiley +1 more source
Novel Bimetallic and Trimetallic Layered Double Hydroxides with the Compositions [Ni<sub>6‑x</sub>Zn <sub><i>x</i></sub> Al<sub>3</sub>(OH)<sub>18</sub>][A(H<sub>2</sub>O)<sub>6</sub>(SO<sub>4</sub>)<sub>2</sub>]·6H<sub>2</sub>O (<i>x</i> from 0 to 6; A= Na<sup>+</sup> o K<sup>+</sup>). [PDF]
Sotiles AR +4 more
europepmc +1 more source
This study presents a transferable modeling framework for carbon capture using aluminosilicates, integrating Universal Isotherm Modeling with experimental data. It reveals how ultramicropores, alumina content, and amine functionalization influence CO2 adsorption energetics.
Pooja Anil Kumar Nair +4 more
wiley +1 more source
Piezoelectricity of layered double hydroxides: perspectives regarding piezocatalysis and nanogenerators. [PDF]
Seliverstov ES +2 more
europepmc +1 more source
Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement
The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang +7 more
wiley +1 more source
Acid neutralization and metal mobilization in oil sands froth treatment tailings. [PDF]
Ferry SR, Abdolahnezhad M, Lindsay MBJ.
europepmc +1 more source
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu +18 more
wiley +1 more source
Fe Incorporation in Ni-Based Layered Hydroxides: Implications for Oxygen Evolution Electrocatalysis. [PDF]
Jaramillo-Hernández C +5 more
europepmc +1 more source
Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng +10 more
wiley +1 more source

