Results 91 to 100 of about 59,669 (311)
Accelerating drug repurposing for COVID-19 via modeling drug mechanism of action with large scale gene-expression profiles [PDF]
arXiv, 2020 The novel coronavirus disease, named COVID-19, emerged in China in December 2019, and has rapidly spread around the world. It is clearly urgent to fight COVID-19 at global scale. The development of methods for identifying drug uses based on phenotypic data can improve the efficiency of drug development.
arxiv
Tumor Diagnosis and Treatment Based on Stimuli‐Responsive Aggregation of Gold Nanoparticles
Exploration, EarlyView.This review summarizes the current strategies for inducing gold nanoparticles aggregation and its advances in tumor diagnosis and treatment. The authors hope this review can provide a valuable reference for the further development of AuNPs clinical applications.
Xiaowei Chang, Huaiyu Wang, Xin Chen
wiley +1 more source
Atherosclerosis Plus, 2023 Background and aims: To evaluate the effect of hydroxychloroquine (HCQ) on serum and lipoprotein lipids and serum biomarkers of cholesterol synthesis and absorption in myocardial infarction patients with a high-dose statin. Methods: Myocardial infarction
Lotta Ulander +12 more
doaj
Modelling and docking of Indian SARS-CoV-2 spike protein 1 with ACE2: implications for co-morbidity and therapeutic intervention [PDF]
arXiv, 2020 Presently, India bears amongst the highest burden of non-communicable diseases such as diabetes mellitus (DM), hypertension (HT), and cardio vascular disease (CVD) and thus represents a vulnerable target to the SARS-CoV-2/COVID-19 pandemic. Involvement of the angiotensin converting enzyme 2 (ACE2) in susceptibility to infection and pathogenesis by SARS-
arxiv
Ibrain, EarlyView.We report a girl with a diagnosis of “neuromyelitis optica spectrum disorder comorbid Sjogren's syndrome” whose condition showed significant improvement after treatment with corticosteroids and immunosuppressive drugs (prednisolone, hydroxychloroquine, and mycophenolate mofetil).
Man‐Min Zhu +3 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To explore the correlation between antinuclear antibodies (ANAs) and pregnancy loss (PL), and to observe its impact on the pregnancy outcomes of in vitro fertilization/intracytoplasmic sperm injection‐embryo transfer (IVF/ICSI‐ET) in recurrent PL (RPL) patients. Methods In this retrospective study, patients first seen at the hospital
Manman Liu +8 more
wiley +1 more source
Autoimmune retinopathy associated with systemic lupus erythematosus: A diagnostic dilemma
Taiwan Journal of Ophthalmology, 2017 Visual loss in systemic lupus erythematosus (SLE) due to autoimmune retinopathy (AIR) is rare and easily misdiagnosed as hydroxychloroquine retinopathy.
Wadakarn Wuthisiri +6 more
doaj +1 more source
Molecular docking and binding mode analysis of selected FDA approved drugs against COVID-19 selected key protein targets: An effort towards drug repurposing to identify the combination therapy to combat COVID-19 [PDF]
arXiv, 2020 The emergence of COVID-19 has severely compromised the arsenal of antiviral and antibiotic drugs. Drug discovery is a multistep process with a high failure rate, high cost and it takes approximately 10-12 years for the development of new molecules into the clinical candidate. On the other side, drug repurposing also called old drugs for new uses, is an
arxiv
Subcutaneous Panniculitis‐like T‐cell Lymphoma
Arthritis &Rheumatology, Accepted Article.
Shae Chambers +2 more
wiley +1 more source
European Journal of Neurology, Volume 30, Issue 2, Page 399-412, February 2023., 2023 Abstract Background and purpose Clinical outcome information on patients with neuromuscular diseases (NMDs) who have been infected with SARS‐CoV‐2 is limited. The aim of this study was to determine factors associated with the severity of COVID‐19 outcomes in people with NMDs.
Chiara Pizzamiglio +93 more
wiley +1 more source