Results 101 to 110 of about 115,105 (360)

Novel Coronavirus (2019-nCoV) in Disguise [PDF]

, 2020
Novel coronavirus (2019-nCoV) pandemic is currently one of the most influential topics as it not only impacts the field of medicine but most importantly, it affects the lives of many individuals throughout the world.
Abideen, Zain U., Douglas, Annyella, Khanal, Shristi, Tzarnas, Stephanie, Zhang, Qian   +4 more
core   +2 more sources

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Effect of Hydroxychloroquine and Azithromycin on QT Interval Prolongation and Other Cardiac Arrhythmias in COVID-19 Confirmed Patients

Cardiovascular Therapeutics, 2021
Background. Hydroxychloroquine with or without azithromycin was one of the common therapies at the beginning of the COVID-19 pandemic. They can prolong QT interval, cause torsade de pointes, and lead to sudden cardiac death.
Seyed Parsa Eftekhar, Sohrab Kazemi, Mohammad Barary, Mostafa Javanian, Soheil Ebrahimpour, Naghmeh Ziaei   +5 more
doaj   +1 more source

Screening for chloroquine maculopathy in populations with uncertain reliability in outcomes of automatic visual field testing [PDF]

, 2016
Purpose: The purpose of this study was to compare screening methods for the early detection of maculopathy in patients treated with chloroquine (CQ) or hydroxychloroquine (HCQ) and to identify the risk factors for the development of toxic maculopathy ...
Chavengsaksongkram, P. (Pimploy), Kunavisarut, P. (Paradee), Pathanapitoon, K. (Kessara), Rothová, A. (Aniki)   +3 more
core   +5 more sources

Comparative study between the therapeutic effect of Remdesivir versus Hydroxychloroquine in Covid-19 hospitalized patients. [PDF]

, 2021
Maii Shams Eldeen, Mohamed Abdelghafar, Hoda Ibrahim, Alshimaa Aboalsoud, Marwa Taha   +4 more
openalex   +1 more source

Effect of Hydroxychloroquine in Hospitalized Patients with COVID-19: Preliminary results from a multi-centre, randomized, controlled trial.

medRxiv, 2020
Background: Hydroxychloroquine and chloroquine have been proposed as treatments for coronavirus disease 2019 (COVID-19) on the basis of in vitro activity, uncontrolled data, and small randomized studies.
P. Horby, M. Mafham, L. Linsell, Jennifer L Bell, N. Staplin, J. Emberson, M. Wiselka, A. Ustianowski, E. Elmahi, B. Prudon, Anthony Whitehouse, T. Felton, John Williams, Jakki Faccenda, J. Underwood, J. Baillie, L. Chappell, S. Faust, T. Jaki, K. Jeffery, W. Lim, A. Montgomery, K. Rowan, J. Tarning, J. Watson, N. J. White, E. Juszczak, Richard Haynes, Martin J. Landray   +28 more
semanticscholar   +1 more source

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

Advanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang, Lijuan Wang, Dianwen Han, Peng Su, Bing Chen, Wenjing Zhao, Tong Chen, Ning Zhang, Xiaolong Wang, Yiran Liang, Yaming Li, Chen Li, Xi Chen, Dan Luo, Qifeng Yang   +14 more
wiley   +1 more source

Renoprotective Effects of Hydroxychloroquine and Folinic Acid via ET-1 and NLRP3 Modulation in Reducing Tubular Injury in A Rabbit Model of Methanol-induced Acute Kidney Injury

Indonesian Biomedical Journal
BACKGROUND: Methanol intoxication is associated with significant morbidity and mortality, particularly when acute kidney injury (AKI) developed. Emerging evidence implicates Endothelin-1 (ET-1) and Nucleotide-binding domain leucine-rich repeat-containing
Prayuda Prayuda, I Gde Raka Widiana, Ketut Suega, Yenny Kandarini, Ni Wayan Winarti, Bambang Purwanto   +5 more
doaj   +1 more source

Hydroxychloroquine and tocilizumab therapy in COVID-19 patients-An observational study.

PLoS ONE, 2020
Hydroxychloroquine has been touted as a potential COVID-19 treatment. Tocilizumab, an inhibitor of IL-6, has also been proposed as a treatment of critically ill patients.
Andrew Ip, Donald A Berry, Eric Hansen, Andre H Goy, Andrew L Pecora, Brittany A Sinclaire, Urszula Bednarz, Michael Marafelias, Scott M Berry, Nicholas S Berry, Shivam Mathura, Ihor S Sawczuk, Noa Biran, Ronaldo C Go, Steven Sperber, Julia A Piwoz, Bindu Balani, Cristina Cicogna, Rani Sebti, Jerry Zuckerman, Keith M Rose, Lisa Tank, Laurie G Jacobs, Jason Korcak, Sarah L Timmapuri, Joseph P Underwood, Gregory Sugalski, Carol Barsky, Daniel W Varga, Arif Asif, Joseph C Landolfi, Stuart L Goldberg   +31 more
doaj   +1 more source

Toxidermie médicamenteuse sous hydroxychloroquine pour traitement systémique d´un syndrome de Goujerot Sjögren primaire: rapport de cas

The Pan African Medical Journal, 2021
Nous rapportons un cas d´exanthème maculo-papuleux apparu après une semaine de prise de l´hydroxychloroquine 400mg prescrite pour une atteinte articulaire d´un syndrome de Goujerot Sjögren primaire chez une patiente de 41 ans.
Ansumana Mohammed Keita, Mouna Zahlane, Laila Benjilali, Lamiaa Essaadouni   +3 more
doaj   +1 more source