Results 181 to 190 of about 57,632 (243)

Whipple Disease Masked by Common Abdominal Pathologies: A Case Report From a Resource‐Constrained Setting

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Whipple disease is a rare multisystem infection that may be overlooked when common gastrointestinal disorders seem to explain symptoms. A 45‐year‐old woman presented with a 2‐year history of postprandial upper abdominal pain, chronic non‐bloody diarrhea, weight loss, and migratory arthralgia.
Amanuel Mesfin Oljira   +7 more
wiley   +1 more source

Methotrexate Toxicity in a Patient With Renal Failure Despite a Normal Methotrexate Concentration: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Methotrexate (MTX) is a folate antagonist widely used as a disease‐modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA), as well as in several malignancies and autoimmune disorders. Although low‐dose MTX (5–20 mg/week) is generally considered safe, it has a narrow therapeutic index, and toxicity can occur even at therapeutic doses,
Fatemeh Afra   +7 more
wiley   +1 more source

Recurrent Acute Limb Ischaemia due to Malignant Thromboembolism Involving Bilateral Lower Limbs Simultaneously

open access: yesCancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Acute Limb Ischaemia (ALI) is a limb and life‐threatening condition that is often associated with cardiovascular disease, atrial fibrillation (AF), diabetes and smoking. It is less commonly associated with active malignancy. There is growing evidence regarding this association.
Amos Au, Audrey Choy, Ming Yii
wiley   +1 more source

Lysine lactylation‐mediated post‐translational modification: Molecular mechanisms and therapeutic target exploration in tumour drug resistance

open access: yesClinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Lysine lactylation (Kla) serves as a metabolic–epigenetic switch governed by writer–eraser–reader regulatory systems, directly connecting the Warburg effect to diverse forms of tumour drug resistance. Intratumoural lactylation critically contributes to treatment failure in chemotherapy, targeted therapy and immunotherapy.
Juan Li   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy