Results 331 to 340 of about 106,358 (395)

Low Dose Methotrexate Has Divergent Effects on Cycling and Resting Human Hematopoietic Stem and Progenitor Cells

open access: yesClinical and Translational Science, Volume 18, Issue 5, May 2025.
ABSTRACT Low dose methotrexate (LD‐MTX) remains the gold standard in rheumatoid arthritis (RA) therapy. Multiple mechanisms on a variety of immune cells contribute to the anti‐inflammatory effects of LD‐MTX. Inflammatory signaling is deeply implicated in hematopoiesis by regulating hematopoietic stem and progenitor cell (HSPC) fate decisions; raising ...
Maximilien Lora   +5 more
wiley   +1 more source

Clinical features, treatment options and outcomes in primary cutaneous B‐cell lymphomas: a real‐world, multicenter, retrospective study

open access: yesInternational Journal of Dermatology, Volume 64, Issue 5, Page 882-889, May 2025.
Clinical features, treatment options and outcomes in PCBCL. Abstract Background Primary cutaneous B‐cell lymphomas (PCBCLs) are rare cutaneous neoplasms with limited literature regarding treatment options and associated treatment outcomes. This study aimed to investigate and present real‐world treatment outcomes in patients with PCBCLs.
Vasiliki Nikolaou   +24 more
wiley   +1 more source

Dermatologic manifestations of hereditary hemochromatosis: A systematic review

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 976-986, May 2025.
Abstract Hereditary hemochromatosis (HH) is a genetic disorder leading to excessive iron absorption, impacting multiple organs, notably the skin, nails and mucosae. The objective of this study is to elucidate the dermatologic manifestations, associated symptoms, pathophysiology and management recommendations of HH.
Hossein Akbarialiabad   +3 more
wiley   +1 more source

Breastfeeding in women with juvenile idiopathic arthritis: results from a Norwegian quality register. [PDF]

open access: yesBMC Pregnancy Childbirth
Birkeland T   +4 more
europepmc   +1 more source

Plasma cell‐directed therapies induce profound clinical and durable responses in patients with severe or relapsed/refractory scleromyxedema

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 1011-1016, May 2025.
In severe forms of monoclonal gammapathy associated with scleromyxoedema with dermatoneuro syndrome and/or cardiac involvement, deep and durable responses allowing IVIG withdrawal could be achieved using anti‐plasma cell therapy, including Imids, anti‐CD38 or proteasome inhibitors. Abstract Background Scleromyxedema (SM) is a rare skin disorder related
F. Theves   +12 more
wiley   +1 more source

Efficacy and safety of CFTR modulators in patients with interstitial lung disease caused by ABCA3 transporter deficiency. [PDF]

open access: yesERJ Open Res
Le Brun M   +13 more
europepmc   +1 more source

New Diagnosis of Lupus Nephritis in the Third Trimester—A Case Report

open access: yesNephrology, Volume 30, Issue 5, May 2025.
ABSTRACT New‐onset lupus nephritis (LN) poses a diagnostic and management challenge during pregnancy. This is more pertinent in the indigenous population, where the prevalence is higher, and the clinical phenotype tends to be more severe. We report the case of a 30‐year‐old G3P2 indigenous female, living in remote Queensland, with a late presentation ...
Umesha Pathmanathan   +6 more
wiley   +1 more source

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