Results 51 to 60 of about 70,027 (183)

Hydroxychloroquine improves manifestation of PE rats under oxidative stress by regulating the PI3K/AKT/mTOR signaling pathway to inhibit autophagy

Scientific Reports
Preeclampsia is currently thought to be characterized by placental oxidative stress damage. Hydroxychloroquine is known to have antioxidant effects, but there are fewer studies on hydroxychloroquine in oxidative stress in preeclampsia. The main objective
Wu Han, Xu Jing, Chu XiaoYan, Huang Wen Wen, Fan Xia, Ren Qin Qin, Wang Ying, Li Xia, Wang Man, Wang Xiu   +9 more
doaj   +1 more source

Heterogeneity in susceptibility to hydroxychloroquine of SARS-CoV-2 isolates

Frontiers in Bioscience-Landmark, 2021
Background: Despite the fact that the clinical efficacy of hydroxychloroquine is still controversial, it has been demonstrated in vitro to control SARS-CoV-2 multiplication on Vero E6 cells.
Celine Boschi, Marion Le Bideau, Julien Andreani, Sarah Aherfi, Priscilla Jardot, Jeremy Delerce, Mathieu Gendrot, Bruno Pradines, Philippe Colson, Anthony Levasseur, Bernard La Scola   +10 more
doaj   +1 more source

Hydroxychloroquine: Looking into the Future

, 2017
Hydroxychloroquine, an antimalarial agent has also been found to possess antidiabetic action. Onset of type-2 diabetes (T2DM) and cardiovascular disease is now considered to be the outcome of systemic inflammation.
Indranil Purkait, Anil Pareek, Saibal Chakravorty, Avinash Talware   +3 more
core   +1 more source

Hydroxychloroquine shortened hospital stay and reduced intensive care unit admissions in hospitalized COVID-19 patients

Journal of Infection in Developing Countries, 2022
Introduction: Effectiveness of hydroxychloroquine against SARS-CoV-2 has been highly controversial. In our research, we aimed to investigate the effects of hydroxychloroquine on disease outcomes in hospitalized patients with COVID-19.
Ahmet Omma, Abdulsamet Erden, Hakan Apaydin, Meryem Aslan, Hüseyin Çamlı, Enes Seyda Şahiner, Serdar Can Güven, Berkan Armağan, Selma Karaahmetoğlu, Ihsan Ates, Orhan Kucuksahin   +10 more
doaj   +1 more source

Hydroxychloroquine-induced acute psychosis in a systemic lupus erythematosus female

, 2011
Hsu WY, Chiu NY, Huang SS. Hydroxychloroquine-induced acute psychosis in a systemic lupus erythematosus female.Background: Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease.
WenYu Hsu, NanYing Chiu, SiSheng Huang
core   +1 more source

Revisiting the cardiovascular risk of hydroxychloroquine in RA

, 2020
International audienceCardiac toxicity can be induced by hydroxychloroquine, especially when used in combination with azithromycin. Interest in hydroxychloroquine and azithromycin as potential therapies for COVID-19 has renewed concerns about the ...
Pers, Yves-Marie, Padern, Guillaume
core   +1 more source

Disposition and Absorption of Hydroxychloroquine Enantiomers Following a Single-Dose of the Racemate

, 1994
The disposition of hydroxychloroquine enantiomers has been investigated in nine patients with rheumatoid arthritis following administration of a single dose of the racemate.
Tett, SE, Day, RO, McLachlan, AJ, Cutler, DJ   +3 more
core   +1 more source

Hydroxychloroquine Is Being Studied As A Way To Treat Coronavirus

, 2020
NPR's Noel King talks to medicinal chemist Katherine Seley-Radtke about hydroxychloroquine, a malaria and arthritis drug touted by the president as a COVID-19 remedy with limited clinical evidence.https://www.npr.org/2020/04/08/829575826 ...
Seley-Radtke, Katherine, King, Noel
core   +1 more source

Examination of patient characteristics and hydroxychloroquine use based on the US Food and Drug Administration’s recommendation: a cross-sectional analysis in New York

BMJ Open, 2021
Objective To describe the pattern of hydroxychloroquine use and examine the association between hydroxychloroquine use and clinical outcomes arising from changes in the US Food and Drug Administration (FDA)’s recommendation during the coronavirus disease
, Sonali Narain, Charlotte Kvasnovsky, Joseph Conigliaro, Martin Lesser, Eun Ji Kim, Kevin Coppa, Jamie S Hirsch, Sara Abrahams, Jennifer Johnson, Karina W Davidson, Stuart L Cohen, Stephen C Machnicki, Alex Makhnevich, Prashant Malhotra, Lyndonna Marrast, Ramanak Mitra, Ernesto P Molmenti, M Wasif Saif, Sanjaya Satapathy, Shalin Shah   +20 more
doaj   +1 more source

Effect of hydroxychloroquine and azithromycin combination use in COVID-19 patients – An umbrella review

Indian Journal of Community Medicine
Background: Hydroxychloroquine and Azithromycin combination was used rampantly in management of COVID-19 patients in different countries. Present review was conducted to evaluate the efficacy of Hydroxychloroquine and Azithromycin combination compared to
Kaushik Nag, Kaushik Tripura, Anjan Datta, Nabarun Karmakar, Manvi Singh, Meenu Singh, Kusum Singal, Pranita Pradhan   +7 more
doaj   +1 more source