Human Chorionic Gonadotropin (hCG) Injections Exacerbating Acute Intermittent Porphyria in a 34-Year-Old Woman. [PDF]
Ali M, Iqbal S.
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A novel acquired resistance mechanism to 5-aminolevulinic acid-mediated photodynamic therapy with ABCG2 inhibition. [PDF]
Chandratre S, Olsen J, Chen B.
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Congenital Erythropoietic Porphyria with Persistent Severe Biochemical Abnormalities and a Non-Mutilating Clinical Course: A Case Report. [PDF]
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Metabolic engineering of <i>Bacillus subtilis</i> for the production of active hemoglobins and myoglobins by improving heme supply. [PDF]
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Genomic Identification and Biochemical Characterization of Methyl Jasmonate (MJ)-Inducible Terpene Synthase Genes in Lettuce (<i>Lactuca sativa</i> L. cv. Salinas). [PDF]
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Reconstructing the hydrogenobyrinic acid synthetic toolkit by combining cell-free systems and metabolic engineering. [PDF]
Lv R, Kang Q, Wang J, Luo X, Zhang D.
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Journal of Molecular Graphics and Modelling, 2020Hydroxymethylbilane synthase (HMBS) is one of the key enzymes of the heme biosynthetic pathway that catalyzes porphobilinogen to form the linear tetrapyrrole 1-hydroxymethylbilane through four intermediate steps. Mutations in the human HMBS (hHMBS) can lead to acute intermittent porphyria (AIP), a lethal metabolic disorder.
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