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Convenient synthesis of 3-Hydroxyquinolines via dakin oxidation: A short synthesis of Jineol

, 2020
A convenient synthesis of 3-hydroxyquinolines has been described via unprecedented Dakin oxidation of quinoline-3-carboxaldehydes. Subsequently, application of the methodology to a high yielding synthesis of quinoline alkaloid Jineol (1) is reported.
S. Ghorai   +8 more
semanticscholar   +1 more source

Reversal of Reactivity of Heyns Intermediate for the Concise Synthesis of Substituted 3-Hydroxyquinolines.

Journal of Organic Chemistry
An efficient and general method for the synthesis of 3-hydroxyquinolines has been achieved from o-acylanilines and α-hydroxyketones in good yields. The strategy involves the intramolecular reverse trapping of the in situ generated aminoenol intermediate ...
Minakshi Altia, P. Anbarasan
semanticscholar   +1 more source

Tailoring the use of 8-Hydroxyquinolines for the Facile Separation of Iron, Dysprosium and Neodymium.

ChemSusChem
Permanent magnets (PMs) containing rare earth elements (REEs) can generate energy in a sustainable manner. With an anticipated tenfold increase in REEs demand by 2050, one of the crucial strategies to meet the demand is developing of efficient recycling ...
Matteo Melegari   +9 more
semanticscholar   +1 more source

Structure-activity relationships of anticancer ruthenium(II) complexes with substituted hydroxyquinolines.

European journal of medicinal chemistry, 2018
8-Hydroxyquinolines (HQ), including clioquinol, possess cytotoxic properties and are widely used as ligands for metal-based anticancer drug research. The number and identity of substituents on the HQ can have a profound effect on activity for a variety ...
D. Havrylyuk   +5 more
semanticscholar   +1 more source

Hydroxyquinolines as Iron Chelators

Current Medicinal Chemistry, 2003
The interest in synthetic siderophore mimics includes therapeutic applications (iron chelation therapy), the design of more effective agents to deliver Fe to plants and the development of new chemical tools for studies of iron metabolism and for a better understanding of iron assimilation processes in living systems.
J-L, Pierre, P, Baret, G, Serratrice
openaire   +2 more sources

Catalyst-Free Synthesis of 2-Anilinoquinolines and 3-Hydroxyquinolines via Three-Component Reaction of Quinoline N-Oxides, Aryldiazonium Salts, and Acetonitrile.

Journal of Organic Chemistry, 2019
A rapid microwave-assisted, catalyst-free, three-component synthesis of various 2-anilinoquinolines from quinoline N-oxides and aryldiazonium salts in acetonitrile under microwave irradiation is reported.
A. Dhiman   +3 more
semanticscholar   +1 more source

Enthalpies of combustion, vapour pressures, and enthalpies of sublimation of 2-hydroxyquinoline, 4-methyl-2-hydroxyquinoline, 4-hydroxyquinoline, and 2-methyl-4-hydroxyquinoline

The Journal of Chemical Thermodynamics, 1990
Abstract The standard (po = 0.1 MPa) molar enthalpies of formation were derived from the standard molar enthalpies of combustion, in oxygen, at 298.15 K, measured by static bomb calorimetry for 2-hydroxyquinoline (2HOQ), 4-methyl-2-hydroxyquinoline (4Me-2HOQ), 4-hydroxyquinoline (4HOQ), and 2-methyl-4-hydroxyquinoline (2Me-4HOQ); the vapour pressures
Manuel A.V Ribeiro da Silva   +2 more
openaire   +1 more source

Investigation of intramolecular hydrogen bonding in conjunction with cation-π interactions in complexes involving 4-substituted-8-hydroxyquinolines

Journal of Molecular Structure, 2019
Intramolecular hydrogen bonding interactions together with non-covalent cation-π interactions of the Na+ cation in 4-substituted-8-hydroxyquinolines were investigated using quantum mechanical calculations to know results of reciprocal effects of these ...
P. Karimi
semanticscholar   +1 more source

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