Prédétermination des débits maximaux de crue par simulation Monte-Carlo de la pluie nette [PDF]
, 2006 Une méthodologie a été proposée pour la prédétermination des débits à partir de la pluviométrie. Il s’agit d’associer, en entrée, les simulations Monte Carlo de hyétogrammes de pluie nette avec un modèle d’hydrogramme unitaire à base de géomorphologie ...
Bargaoui, Zoubeida Kebaili +1 more
core +1 more source
Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma.
New England Journal of Medicine, 2020 BACKGROUND The combination of atezolizumab and bevacizumab showed encouraging antitumor activity and safety in a phase 1b trial involving patients with unresectable hepatocellular carcinoma. METHODS In a global, open-label, phase 3 trial, patients with
R. Finn +20 more
semanticscholar +1 more source
Selection of hydrological probability distributions for extreme rainfall events in the regions of Colombia [PDF]
, 2020 Frequency analysis of extreme events is used to estimate the maximum rainfall associated with different return periods and is used in planning hydraulic structures.
Coronado Hernández, Jairo Rafael +3 more
core +1 more source
Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma.
New England Journal of Medicine, 2021 BACKGROUND The efficacy and safety of nivolumab plus cabozantinib as compared with those of sunitinib in the treatment of previously untreated advanced renal-cell carcinoma are not known.
T. Choueiri +30 more
semanticscholar +1 more source
Overall Survival with Ribociclib plus Letrozole in Advanced Breast Cancer.
New England Journal of Medicine, 2022 BACKGROUND In a previous analysis of this phase 3 trial, first-line ribociclib plus letrozole resulted in significantly longer progression-free survival than letrozole alone among postmenopausal patients with hormone receptor (HR)-positive, human ...
G. Hortobagyi +19 more
semanticscholar +1 more source
Lenvatinib plus Pembrolizumab for Advanced Endometrial Cancer.
New England Journal of Medicine, 2022 BACKGROUND Standard therapy for advanced endometrial cancer after failure of platinum-based chemotherapy remains unclear. METHODS In this phase 3 trial, we randomly assigned, in a 1:1 ratio, patients with advanced endometrial cancer who had previously ...
V. Makker +23 more
semanticscholar +1 more source
Understanding the drivers of sustainable land expansion using a patch-generating land use simulation (PLUS) model: A case study in Wuhan, China [PDF]
Computers, Environment and Urban Systems, 2020 Cellular Automata (CA) are widely used to model the dynamics within complex land use and land cover (LULC) systems. Past CA model research has focused on improving the technical modeling procedures, and only a few studies have sought to improve our ...
Xun Liang +5 more
semanticscholar +1 more source
Genomics, Proteomics & Bioinformatics, 2022 Combinatorial therapies have been recently proposed to improve the efficacy of anticancer treatment. The SynergyFinder R package is a software used to analyze pre-clinical drug combination datasets.
Shuyu Zheng +6 more
semanticscholar +1 more source
Pembrolizumab plus Chemotherapy in Metastatic Non–Small‐Cell Lung Cancer
New England Journal of Medicine, 2018 BACKGROUND First‐line therapy for advanced non–small‐cell lung cancer (NSCLC) that lacks targetable mutations is platinum‐based chemotherapy. Among patients with a tumor proportion score for programmed death ligand 1 (PD‐L1) of 50% or greater ...
L. Gandhi +28 more
semanticscholar +1 more source
Calcul des hydrogrammes de crues et analyse fréquentielle des données hydro-pluviométriques dans le bassin versant de l’Oued Isser (Nord Algérie) [PDF]
, 2021 L’hydrogramme de crue est une information trop importante dans la réalisation des projets pour prévenir les crues, dans le but de la protection des ouvrages et leurs dimensionnements ainsi que pour éviter les risques de catastrophe.
BOUKAMOUM, Thilali +1 more
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