Results 121 to 130 of about 2,125 (176)
Initiation Setting and Persistence of Medications Affecting Cognition in Older Adults. [PDF]
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Radioimmunoassay for Atropine and l‐Hyoscyamine
Acta Pharmacologica Et Toxicologica, 1980Abstract:A simple, specific and sensitive radioimmunoassay is described for atropine (dl‐hyoscyamine) and l‐hyoscyamine. Antiserum was obtained from rabbits immunized with an immunogen prepared by coupling l‐hyoscyamine to human serum albumin. By using3H‐atropine as tracer, the assay can detect atropine and l‐hyoscyamine concentrations down to 9 nmol/1
R, Virtanen, J, Kanto, E, Iisalo
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Nature, 1954
THE biogenetic origin of the tropane bases has recently been the subject of some discussion1,2, Mortimer1 suggesting that the tropane skeleton may be derived from the breakdown products of tryptophan metabolism. This novel idea is contrary to the accepted hypothesis that a base such as tropine is produced in vivo by reactions analogous to the in vitro ...
E, LEETE, L, MARION, I D, SPENSER
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THE biogenetic origin of the tropane bases has recently been the subject of some discussion1,2, Mortimer1 suggesting that the tropane skeleton may be derived from the breakdown products of tryptophan metabolism. This novel idea is contrary to the accepted hypothesis that a base such as tropine is produced in vivo by reactions analogous to the in vitro ...
E, LEETE, L, MARION, I D, SPENSER
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Journal of Mental Science, 1881
I venture to offer my experience of the use of the above drug for the purpose of comparison with that of other observers. I am anxious not to appear as an advocate of this or any other medicine, having a rather limited faith in the efficacy of drugs in the treatment of disease.
G. M. Bacon, null Hills
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I venture to offer my experience of the use of the above drug for the purpose of comparison with that of other observers. I am anxious not to appear as an advocate of this or any other medicine, having a rather limited faith in the efficacy of drugs in the treatment of disease.
G. M. Bacon, null Hills
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The biosynthesis of hyoscyamine: the process by which littorine rearranges to hyoscyamine
Journal of the Chemical Society, Perkin Transactions 1, 1995The incorporation of isotope from specifically-labelled 3-phenyllactic acid 4 or littorine 7 into 3α-phenylacetoxytropane 10, 3α-phenylacetoxy-6β,7β-epoxytropane and 3α-(2′-hydroxyacetoxy)-tropane 9 has been demonstrated. Transformed root cultures of Datura stramonium or Brugmansia (Datura) Candida x B.
Richard J. Robins +5 more
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Cholinergic Activity of Hyoscyamine
Nature, 1961MANY former and recent investigations, employing various clinical and experimental tests1–4, have already revealed the synergic action of small atropine doses with acetylcholine. We were able to demonstrate quite an unexpected experimental correlation between hyoscyamine and cholinergic activity.
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(−)-Hyoscyamine in Duboisia hopwoodii
Phytochemistry, 1971Tropane alkaloids were found in Duboisia hopwoodii F. Muell. Their location was restricted to the roots of the plant. The pyridine alkaloids were concentrated in its leaves. All Duboisia species therefore, have unexpectedly similar alkaloids but locate them differently within the plant.
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