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Atropin, Daturin und Hyoscyamin [PDF]

open access: yesJournal für Praktische Chemie
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Biogenesis of Hyoscyamine

Nature, 1954
THE biogenetic origin of the tropane bases has recently been the subject of some discussion1,2, Mortimer1 suggesting that the tropane skeleton may be derived from the breakdown products of tryptophan metabolism. This novel idea is contrary to the accepted hypothesis that a base such as tropine is produced in vivo by reactions analogous to the in vitro ...
E, LEETE, L, MARION, I D, SPENSER
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