Results 91 to 100 of about 10,766,583 (291)

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin   +13 more
wiley   +1 more source

The role of income in money demand during hyper-inflation: the case of Yugoslavia [PDF]

open access: yes
During extreme hyper-inflations productivity tends to fall dramatically. Yet, in models of money demand in hyper-inflation variables such as real income has been given a somewhat passive role, either assuming it exogenous or to have a negligible role. In
Bent Nielsen, Zorica Mladenovic
core  

SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition

open access: yesAdvanced Science, EarlyView.
The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhijing Zhang   +9 more
wiley   +1 more source

Comparison of the hyper-cvad with an institutional regimen for the treatment of acute lymphoblastic leukemia in adults in a hospital of Mexico

open access: yesRevista Peruana de Medicina Experimental y Salud Pública, 2014
In order to assess the mortality and toxicity of the Hyper-CVAD protocol used as first-line treatment of acute lymphoblastic leukemia, a retrospective cohort study was performed in patients less than 40 years of age from March to September 2011 treated ...
Christian Omar Ramos-Peñafiel   +12 more
doaj   +1 more source

Classification of Proper Hyper BCI-Algebras of Order 3 [PDF]

open access: yes, 2015
: We consider the notion of an isomorphism between two hyper BCI-algebras and obtain all of the hyper BCI-algebras of order 3. It is shown that there exist 14 proper hyper BCI-algebras and 5 proper weak hyper BCI-algebras of order 3 up to isomorphism ...
Xiaoyan Mao   +3 more
core   +1 more source

Flexible Integration of Structurally Diverse Spatial Multi‐Omics With AgaeSMO

open access: yesAdvanced Science, EarlyView.
AgaeSMO is a versatile and robust deep learning framework for flexible cross‐integration of spatial multi‐omics data. Leveraging a GATs network with a graph attention module, it learns joint embedding across diverse modalities, enabling integration of both structurally paired (e.g., spatial transcriptome‐epigenome, transcriptome‐proteome, transcriptome‐
Kunpeng Liu   +9 more
wiley   +1 more source

A Hyper-Dual Number Approach to Higher-Order Derivative Computation

open access: yesAxioms
This paper develops a theoretical framework for the computation of higher-order derivatives based on the algebra of hyper-dual numbers. Extending the classical dual number system, hyper-dual numbers provide a natural and rigorous mechanism for encoding ...
Ji Eun Kim
doaj   +1 more source

The Hyper-Wiener Index of Trees of Order n with Diameter d

open access: yesDiscrete Dynamics in Nature and Society, 2016
The hyper-Wiener index is a kind of extension of the Wiener index, used for predicting physicochemical properties of organic compounds. The hyper-Wiener index WW(G) is defined as WW(G)=1/2∑u,v∈VGdGu,v+dG2u,v with the summation going over all pairs of ...
Gaixiang Cai   +4 more
doaj   +1 more source

Hyper-induced genes of interest.

open access: yes, 2023
Borrelia burgdorferi (Bb), the causative agent of Lyme disease, establishes a long-term infection and leads to disease manifestations that are the result of host immune responses to the pathogen.
Linden T. Hu (13989808)   +5 more
core   +1 more source

From Artificial to Embodied and Physical Intelligence in Smart Manufacturing

open access: yesAdvanced Science, EarlyView.
Smart manufacturing is reframed through complementary artificial, embodied, and physical intelligence, spanning computational reasoning, perception‐action coupling, and material‐level adaptation. Their integration across design, fabrication, operation, and maintenance reveals how intelligence can be co‐designed across algorithms, embodied agents, and ...
Kang Wang   +9 more
wiley   +1 more source

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