Results 231 to 240 of about 10,766,583 (291)

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Minimising mutation load as a mechanism for low-dose hyper-radiosensitivity and induced radioresistance. [PDF]

Sci Rep
Polgár S, Madas BG.
europepmc   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source

Arthropod Assemblages in Desert Ecosystems of Alula County, Saudi Arabia. [PDF]

Ecol Evol
van Mazijk R, McGregor S, Duker R, Liversage W, Butynski C, Schutgens M, Schleicher M, Graham MD, Rees SK, Aldabaa A, Mohamed AH, Almalki SD, Lee BPY.   +12 more
europepmc   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

Medicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo, Kaeun Chae, Jueun Lee, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Magnetic amino-functionalized hyper-crosslinked resin as a reusable adsorbent for methylene blue. [PDF]

Sci Rep
Cirillo C, Iuliano M, Modestino M, Galluzzi A, Olivieri F, Castaldo R, Gentile G, Polichetti M, Sarno M.   +8 more
europepmc   +1 more source

Extending the hyper‐logistic model to the random setting: New theoretical results with real‐world applications

Mathematical Methods in the Applied Sciences, EarlyView.
We develop a full randomization of the classical hyper‐logistic growth model by obtaining closed‐form expressions for relevant quantities of interest, such as the first probability density function of its solution, the time until a given fixed population is reached, and the population at the inflection point.
Juan Carlos Cortés, Ana Navarro‐Quiles, Sorina Madalina Sferle   +2 more
wiley   +1 more source

Projecting the real through active inference: a unified model of reality construction from neuronal dynamics to social consensus <i>a neuroscientific framework for psychopathology</i>. [PDF]

Front Psychiatry
G P, P P.
europepmc   +1 more source

OpenMRF: A Modular, Vendor‐Neutral Open‐Source Framework for Magnetic Resonance Fingerprinting Using Pulseq

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Widespread adoption and methodological advancement of magnetic resonance fingerprinting (MRF) are limited by the lack of unified, reproducible implementation frameworks and fragmented open‐source tools. To address these barriers, we introduce OpenMRF—a comprehensive Pulseq‐based solution—designed to enable standardized and transferable
Tom Griesler, Jannik Stebani, Sydney Kaplan, Ivaylo Angelov, Petra Albert, Tobias Wech, Martin Blaimer, Xiang Wang, Qingping Chen, Maxim Zaitsev, Zhibo Zhu, Qi Liu, Peter Martin, Jon‐Fredrik Nielsen, Jesse I. Hamilton, Peter Nordbeck, Nicole Seiberlich, Maximilian Gram   +17 more
wiley   +1 more source