Results 71 to 80 of about 160,667 (260)
A Hyper-Dual Number Approach to Higher-Order Derivative Computation
AxiomsThis paper develops a theoretical framework for the computation of higher-order derivatives based on the algebra of hyper-dual numbers. Extending the classical dual number system, hyper-dual numbers provide a natural and rigorous mechanism for encoding ...
Ji Eun Kim
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Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress
Advanced Science, EarlyView.Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen +11 more
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Advanced Science, EarlyView.Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu +9 more
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Revista Peruana de Medicina Experimental y Salud Pública, 2014 In order to assess the mortality and toxicity of the Hyper-CVAD protocol used as first-line treatment of acute lymphoblastic leukemia, a retrospective cohort study was performed in patients less than 40 years of age from March to September 2011 treated ...
Christian Omar Ramos-Peñafiel +12 more
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Advanced Science, EarlyView.A serum‐free, air–liquid interface organotypic slice culture model preserves human post‐mortem corpus callosum tissue, successfully recovering from slicing trauma to reflect the donor's underlying disease state. Pairing label‐free Coherent anti‐Stokes Raman scattering (CARS) microscopy with k‐means clustering enables objective, high‐resolution ...
Kasra Roya‐Kouchaki +5 more
wiley +1 more source
Order and hyper-order of entire solutions of linear differential equations with entire coefficients
Electronic Journal of Differential Equations, 2003 In this paper, we investigate the growth of solutions of the differential equation $$ f^{(k)}+A_{k-1}( z)f^{( k-1) }+dots+A_{1}( z) f'+A_{0}(z) f=0, $$ where $A_{0}( z) ,dots, A_{k-1}(z)$ are entire functions with $A_{0}(z) otequiv 0$. We will show that
Benharrat Belaidi, Karima Hamani
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Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations
Advanced Science, EarlyView.Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford +3 more
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The Hyper-Wiener Index of Trees of Order n with Diameter d
Discrete Dynamics in Nature and Society, 2016 The hyper-Wiener index is a kind of extension of the Wiener index, used for predicting physicochemical properties of organic compounds. The hyper-Wiener index WW(G) is defined as WW(G)=1/2∑u,v∈VGdGu,v+dG2u,v with the summation going over all pairs of ...
Gaixiang Cai +4 more
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Advanced Science, EarlyView.In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao +6 more
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The hyper-Zagreb index of cacti with perfect matchings
AKCE International Journal of Graphs and Combinatorics, 2020 Let be a simple connected graph. The hyper-Zagreb index is defined as . A connected graph is a cacti if all blocks of are either edges or cycles. Let be the set of cacti of order with a perfect matching and cycles. In this paper, we determine sharp upper
Hechao Liu, Zikai Tang
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