Results 61 to 70 of about 456,827 (283)

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Comorbid depressive disorders in ADHD. the role of ADHD severity, subtypes and familial psychiatric disorders [PDF]

, 2014
ObjectiveaaTo evaluate the presence of Major Depressive Disorder (MDD) and Dysthymic Disorder (DD) in a sample of Italian children with Attention Deficit Hyperactivity Disorder (ADHD) and to explore specific features of comorbid depressive disorders in ...
Andriola E, Di Roma F, DI TRANI, MICHELA, Donfrancesco R., Leone D, Miano S, PARISI, Pasquale   +6 more
core   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Prenatal Nicotine Exposure as a Teratogen in Neurological Pathways [PDF]

, 2016
Attention-deficit/hyperactivity disorder (ADHD) is the most heritable and commonly diagnosed childhood psychiatric disorder with 4% of all children being diagnosed with this disorder.
Grover, Monica
core   +1 more source

Atypical neural responses to vocal anger in attention-deficit/hyperactivity disorder [PDF]

, 2014
Background Deficits in facial emotion processing, reported in attention-deficit/hyperactivity disorder (ADHD), have been linked to both early perceptual and later attentional components of event-related potentials (ERPs).
Banaschewski, Banaschewski, Banse, Barry, Biederman, Blackburn, Bostanov, Broyd, Bruckmann, Chronaki, Chronaki, Corbett, Corwin, Cullum, D'Agati, Dennis, Dien, Eimer, Fairchild, Goodman, Hogan, Ibáñez, Iredale, Jaaskelainen, Johnston, Johnstone, Johnstone, Johnstone, Konrad, Korpilahti, Kosslyn, Köchel, Köchel, Loiselle, Maurage, Mueller, Nelson, Norvilitis, Oades, Olincy, Pang, Pinheiro, Pinheiro, Putman, Sander, Schirmer, Semlitsch, Shaffer, Shapiro, Shaw, Sonuga-Barke, Stringaris, Toivonen, Uekermann, Wechsler, Williams, Woldorff, Woodman, Wunderlich, Zambelli   +59 more
core   +2 more sources

Purpose‐Adaptable Reinforced 3D Hyaluronic‐Acid Based Platform to Study Pathomechanisms of the Central Nervous System

Advanced Healthcare Materials, EarlyView.
Platform system to create biofabricated 3D spinal cord tissue models: Combining high resolution PCL fiber placement, a customized, hyaluronic acid‐based hydrogel, two cell types (spinal cord neurons and astrocytes) together with three distinct laminin isoforms allow the formation of functional cell–cell network interactions.
Nicoletta Murenu, Esra Tuerker, Anna‐Lena Wiessler, Jessica Faber, Ievgenii Liashenko, Jeanette Weigelt, Jörg Tessmar, Paul D. Dalton, Sibylle Jablonka, Mateo S. Andrade Mier, Carmen Villmann, Silvia Budday, Natascha Schaefer   +12 more
wiley   +1 more source

Working Effectively with People with Attention Deficit/ Hyperactivity Disorder [PDF]

, 2001
This brochure on People with Attention Deficit/Hyperactivity Disorder and the Americans with Disabilities Act (ADA) is one of a series on human resources practices and workplace accommodations for persons with disabilities edited by Susanne M.
Bruyere, Susanne M, Tominey, Eve W, Tominey, Matthew   +2 more
core   +1 more source

Complexity Analysis of Spontaneous Brain Activity in Attention-Deficit/Hyperactivity Disorder: Diagnostic Implications [PDF]

, 2009
Background: Attention-deficit/hyperactivity disorder (ADHD) is defined as the most common neurobehavioral disorder of childhood, but an objective diagnostic test is not available yet to date.
Aboy, Alberto Fernández, Amigo, Anokhin, Anokhin, Barkley, Bock, Bush, Bush, Carlos Gómez, Castellanos, Clarke, Conners, Demanuele, Dickstein, Dockstader, Franciotti, Gogtay, Goldberger, Gomez, Gomez, Hosmer, Hämäläinen, Ilmoniemi, Javier Escudero, Javier Quintero, Jeong, Jeong, Joseph Biederman, Klingberg, Lempel, Loo, Lutzenberger, Marta Navas, Meyer-Lindenberg, Monastra, Mulas, Murias, Natalia García-Campos, Nunez, Oldfield, Osipova, Pilar Zuluaga, Plonsey, Radhakrishnan, Rapoport, Reich, Roberto Hornero, Shaw, Sowell, Sporns, Stam, Stam, Tomás Ortiz, Wienbruch, Willis, Zhang   +56 more
core   +3 more sources

Cap‐oPMN: Oral Inflammatory Load Quantification Using Capillary Microfluidics and Automated Image Processing

Advanced Materials Technologies, EarlyView.
ABSTRACT Quantifying oral polymorphonuclear neutrophils (oPMNs) is a clinically validated approach for assessing periodontal inflammation. However, current methods, such as manual hemocytometry and flow cytometry, are time‐consuming (>3 h), require invasive sampling, and depend on staining and complex instrumentation, making them unsuitable for point ...
Mohsen Hassani, Azam Zare, Fatemeh Soheili, S. M. Mahdi H. Daneshvar, Mahdi Amrollahi Biouki, Yasaman Tahernezhad, Chunxiang Sun, Michael Glogauer, Ebrahim Ghafar‐Zadeh, Amir Sanati‐Nezhad   +9 more
wiley   +1 more source