Results 171 to 180 of about 219,244 (264)

The effect of phosphatidylserine on behavioral problems in children with attention deficit hyperactivity disorder. [PDF]

Front Psychiatry
Shen Z, Jia S, Li X, Jiang X, Zhang H, Fang Y.   +5 more
europepmc   +1 more source

Cognitive and behavioral clinical outcome assessments in children with developmental and epileptic encephalopathies: Issues and instruments

Epilepsia, EarlyView.
Abstract Children with developmental and epileptic encephalopathies (DEEs) face cognitive and behavioral challenges that may have a greater impact than seizures on their quality of life (QoL). The need to assess these nonseizure outcomes for evaluating treatments is increasingly recognized.
Cinzia Correale, Nicola Specchio, Jenny Downs, J. Helen Cross, Simona Cappelletti, Andrea Palacio‐Navarro, Sam Geuens, Kette Valente, Andreas Brunklaus, Colin Reilly   +9 more
wiley   +1 more source

The typology of common psychiatric disorders as depicted by genetic maps: a study based on Swedish population-based registers. [PDF]

World Psychiatry
Kendler KS, Ohlsson H, Amstadter AB, Sundquist J, Sundquist K.   +4 more
europepmc   +1 more source

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

Epilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen, Vivian W. Y. Liao, Tomasz S. Mieszczanek, Anne V. Jakobsen, Elena Gardella, Kern Olofsson, Marina Nikanorova, Allan Bayat, Sebastian Ortiz, Sarah Weckhuysen, Cecilie Johannessen Landmark, Orrin Devinsky, Mary Chebib, Philip K. Ahring, Guido Rubboli, Rikke S. Møller   +15 more
wiley   +1 more source

Effectiveness of Computerized Cognitive Remediation Therapy on Executive Functions and Clinical Symptoms in Children and Adolescents With ADHD: A Meta-Analysis of Randomized Controlled Trials. [PDF]

Alpha Psychiatry
Ye J, Zhang Y, Ma N, Zhou T, Yuan L, Wei Y, Li J, Zheng X, Liu D, Guo J, Xiao A.   +10 more
europepmc   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Inattention and impulsivity in attention-deficit/hyperactivity disorder (ADHD) and pediatric extremity fractures: an association between neurobehavioral traits and trauma presentation. [PDF]

Ulus Travma Acil Cerrahi Derg
Korkmaz T, Afacan MY, Ince Y, Ozer M, Öz F, Talmaç MA.   +5 more
europepmc   +1 more source

De novo TANC2 stop‐loss variant associated with developmental impairment and drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Matthew A. Hintermayer, Kenneth A. Myers
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

The bidirectional relationship between children's bedtime irregularity & hyperactivity/inattention symptoms: a prospective cohort study. [PDF]

BMC Psychol
Li KHA, Wong ML.
europepmc   +1 more source