Results 221 to 230 of about 456,784 (284)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

De novo TANC2 stop‐loss variant associated with developmental impairment and drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Matthew A. Hintermayer, Kenneth A. Myers
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Rapunzel Syndrome in a Child With Sensory Feeding Difficulties and Attention-Deficit Hyperactivity Disorder. [PDF]

Cureus
Lurshay RM, Dunbar A, Suliman O, Lipscomb N.   +3 more
europepmc   +1 more source

Efficacy of neurosurgical interventions for epilepsy in polymicrogyria: A systematic review

Epilepsia Open, EarlyView.
Abstract Polymicrogyria (PMG) is a rare malformation of cortical development (MCD) characterized by abnormal neuronal architecture, often associated with epilepsy. Neurosurgical interventions have been explored, but their effectiveness remains a subject of ongoing research and debate.
Sergio Rinella, Manuela Lo Bianco, Agata Polizzi, Martino Ruggieri, Finbar J. K. O'Callaghan   +4 more
wiley   +1 more source

The Protective Role of Attention-Deficit Hyperactivity Disorder Medication Against Post-disaster Psychopathology in Children: A Naturalistic Study After the 2023 Turkiye Earthquakes. [PDF]

Cureus
Kocak E, Kamis B, Ince N, Varmis DA, Kalınlı EM, Cilogullari E, Sahin K, Inal Ulutas G, Demirci TH, Yuce Antepuzumu EG, Yuksekkaya C, Gunes S.   +11 more
europepmc   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

Exploratory Study: The Impact of Online Coordinative Exercise in a Small Latinx Youth Sample. [PDF]

Pediatr Rep
Hernandez NJ, Carlson JS.
europepmc   +1 more source

Microstructure imaging in patients undergoing evaluation for epilepsy surgery or low‐grade glioma: Clinical utility of a novel diffusion MRI method

Epilepsia Open, EarlyView.
Abstract Objective To investigate a recently developed MRI technique for mapping the Mean Diffusivity of Tissue (MDT), which improves diffusion MRI imaging of the cerebral cortex by reducing partial volume effects from cerebrospinal fluid (CSF). As cortical lesions are common in patients with focal epilepsy, we explored the clinical value of MDT ...
Irena Grubor, Kristina Serednicka, Cornelia Säll, Maria Compagno Strandberg, Markus Nilsson, Johan Bengzon   +5 more
wiley   +1 more source