Results 301 to 310 of about 98,039 (356)

Focus on P2X7R in microglia: its mechanism of action and therapeutic prospects in various neuropathic pain models. [PDF]

Front Pharmacol
Zhang K, Ran R, Zhang CJ, Wang L, Zhang HH.   +4 more
europepmc   +1 more source

Systemic antihyperalgesic effect of a novel conotoxin from Californiconus californicus in an inflammatory pain model. [PDF]

Front Pain Res (Lausanne)
López-Carrillo J, Bernáldez-Sarabia J, Pawar TJ, Jiménez S, Dueñas S, Figueroa-Montiel A, Olivares-Romero JL, Granados-Soto V, Licea-Navarro AF, Caram-Salas NL.   +9 more
europepmc   +1 more source

Rebound Pain After Regional Anaesthesia. [PDF]

Medicina (Kaunas)
Fallon F, Ramly MS, Moorthy A.
europepmc   +1 more source

Modafinil Ameliorated Fibromyalgia Syndrome in Rats by Modulating Mast Cells and Microglia Activation Through Dopamine/Substance P/MRGPRX/Histamine and PI3K/p-Akt/NF-κB Signaling Pathways. [PDF]

J Neuroimmune Pharmacol
Kamal MM, Essam RM, Abdelkader NF, Zaki HF.   +3 more
europepmc   +1 more source

Dyspareunia is rarely assessed in rodent models of endometriosis and interstitial cystitis/bladder pain syndrome. [PDF]

Reprod Fertil
Nunez-Badinez P, Shah R, Demetriou L, De Leo B, Meijlink J, Birch J, Schmidt N, Nagel J, Vincent K.   +8 more
europepmc   +1 more source

Exploring the role of negative expectations and emotions in primary dysmenorrhea: insights from a case-control study. [PDF]

BMC Womens Health
Thomann V, Gomaa N, Stang M, Funke SA, Meissner K.   +4 more
europepmc   +1 more source

Novel Trajectories Towards Possible Effects of Semaglutide for Amelioration of Reserpine-induced Fibromyalgia in Rats: Contribution of cAMP/PKA/p-CREB and M1/M2 Microglia Polarization. [PDF]

J Neuroimmune Pharmacol
Shafiek MZ, Zaki HF, Mohamed AF, Ibrahim WW.   +3 more
europepmc   +1 more source

Nocebo Effect on Pain-Related Autonomic Responses in a State of Experimentally-Induced Sensitization. [PDF]

Eur J Pain
Allmendinger F, Rosner J, Egger T, Scheuren PS, Hubli M.   +4 more
europepmc   +1 more source

Significant hindlimb static weight-bearing asymmetry persists for 40-weeks in a longitudinal study in two widely used rat models of surgically induced osteoarthritis knee pain. [PDF]

Front Pharmacol
Kuo A, Raboczyj A, Nicholson JR, Corradini L, Smith MT.   +4 more
europepmc   +1 more source

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Opioid-Induced Tolerance and Hyperalgesia

CNS Drugs, 2019
Opioids are very potent and efficacious drugs, traditionally used for both acute and chronic pain conditions. However, the use of opioids is frequently associated with the occurrence of adverse effects or clinical problems. Other than adverse effects and dependence, the development of tolerance is a significant problem, as it requires increased opioid ...
Sebastiano Mercadante, Edoardo Arcuri, Angela Santoni   +2 more
openaire   +4 more sources