Results 81 to 90 of about 9,393 (183)

Chronic hyperammonemia alters motor and neurochemical responses to activation of group i metabotropic glutamate receptors in the nucleus accumbens in rats in vivo

Neurobiology of Disease, 2003
Hyperammonemia leads to altered cerebral function and neurological alterations in patients with hepatic encephalopathy. We studied the effects of hyperammonemia in rats on the modulation by group I metabotropic glutamate receptors (mGluR) of motor and ...
Juan-José Canales, Amina Elayadi, Mohammed Errami, Marta Llansola, Omar Cauli, Vicente Felipo   +5 more
doaj   +1 more source

Hyperammonemia impairs long-term potentiation in hippocampus by altering the modulation of cGMP-degrading phosphodiesterase by protein kinase G

Neurobiology of Disease, 2004
Hyperammonemia impairs long-term potentiation (LTP) in hippocampus, by an unknown mechanism. LTP in hippocampal slices requires activation of the soluble guanylate cyclase (sGC)-protein kinase G (PKG)-cGMP-degrading phosphodiesterase pathway.
Pilar Monfort, Marı́a-Dolores Muñoz, Vicente Felipo   +2 more
doaj   +1 more source

Sarcopenia Predicts Mortality and Hepatic Encephalopathy After TIPS in Older Adults With Cirrhosis and Improves Prognostic Scores

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aims The role of transjugular intrahepatic portosystemic shunt (TIPS) in older adults remains controversial because of limited risk‐stratification tools. We aimed to assess whether sarcopenia and myosteatosis are independently associated with post‐TIPS mortality and overt hepatic encephalopathy (OHE) in patients aged ≥ 70 years,
Dario Saltini, Silvia Nardelli, Roberto Miraglia, Davide Roccarina, Stefania Gioia, Federico Banchelli, Luigi Maruzzelli, Cristian Caporali, Gianmarco Falcone, Marcello Bianchini, Tomas Guasconi, Angelica Ingravallo, Simone Di Cola, Rosina Maria Critelli, Fabiola Milosa, Antonio Piscopo, Federico Casari, Andrea Salomé Velasco Mayorga, Filippo Scianò, Giovanni Battinelli, Francesco Ascari, Oliviero Riggio, Fabio Marra, Manuela Merli, Francesco Vizzutti, Filippo Schepis   +25 more
wiley   +1 more source

Fatal hyperammonemia caused by Mycoplasma hominis infection: A rare case report

International Journal of Infectious Diseases
Hyperammonemia, a clinical condition characterized by elevated serum ammonia levels, often leads to altered consciousness and can have severe neurological consequences. It predominantly affects patients with hyperammonemic encephalopathy (HE), urea cycle
Yushi Fan, Lanxin Cao, Tiancha Huang, Chengyang Chen, Hui Shan, Linlin Du, Wei Cui, Gensheng Zhang   +7 more
doaj   +1 more source

Guidelines for acute management of hyperammonemia in the Middle East region

Therapeutics and Clinical Risk Management, 2016
Majid Alfadhel,1,2 Fuad Al Mutairi,1,2 Nawal Makhseed,3 Fatma Al Jasmi,4 Khalid Al-Thihli,5 Emtithal Al-Jishi,6 Moeenaldeen AlSayed,7 Zuhair N Al-Hassnan,7,8 Fathiya Al-Murshedi,5 Johannes Häberle,9 Tawfeg Ben-Omran10 Middle East Hyperammonemia and
Alfadhel M, Al Mutairi F, Makhseed N, Al Jasmi F, Al-Thihli K, Al-Jishi E, AlSayed M, Al-Hassnan ZN, Al-Murshedi F, Häberle J, Ben-Omran T   +10 more
doaj  

Hyperammonemia heightens anesthetic sensitivity in male rats with acute hepatic encephalopathy via affecting brain areas represented by the cerebellum

BMC Anesthesiology
Background Precise anesthesia is essential to ensure perioperative safety in patients with hepatic encephalopathy (HE) due to severe liver injuries. Hyperammonemia has been implicated as a possible trigger for HE.
Sa Wang, Xin-Xin Zhao, Dan Tang, Shi-An Li, Tian-Qi Li, Bing-Xue Peng, Yi-Hao Wang, Sai-Hong Xu, Po Gao, Xue Xue, Ying-Fu Jiao, Yan Zhou, Wei-Feng Yu   +12 more
doaj   +1 more source

Hyperammonemia [PDF]

, 2020
openaire   +1 more source

Postoperative hyperammonemic encephalopathy due to unexpected constipation in a patient with hyperornithinemia-hyperammonemia-homocitrullinuria syndrome: a case report

JA Clinical Reports
Background Hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome is a rare autosomal recessive urea cycle disorder associated with a high risk of exacerbation of hyperammonemia during the perioperative period.
Haruka Tachibana, Nobuhiko Ohashi, Gaku Okumura, Ryusuke Tanaka, Satoshi Fuseya, Sayako Gotoh, Takashi Ishida, Sari Shimizu, Mikito Kawamata, Satoshi Tanaka   +9 more
doaj   +1 more source

The Toll of Hyperammonemia on the Brain [PDF]

Cellular and Molecular Gastroenterology and Hepatology, 2019
Saunders, Justin M., González-Maeso, Javier, Bajaj, Jasmohan S.   +2 more
openaire   +2 more sources

Hyperammonemia associated with low doses and concentrations of valproic acid in older adults with neurocognitive disorder. [PDF]

Ment Health Clin
Coyne S, Das A.
europepmc   +1 more source