Results 41 to 50 of about 43,789 (227)

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation–Energy Axis?

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by a preclinical stage that typically lasts for decades. Early on during this time, microglia react to pathological changes and become protective and even transiently delay neurodegeneration.
Sara Merlo, Cristiana Lucia Rita Lipari, Aurora Patti, Maria Angela Sortino   +3 more
wiley   +1 more source

IL-17 + γδT cell: a new target in hyperbaric oxygen treatment reducing spinal cord injury

Journal of Translational Medicine
Background Hyperbaric oxygen (HBO) treatment can attenuate the inflammatory response after spinal cord injury (SCI), but the specific molecular mechanisms are unclear. γδT cells have emerged as key immune regulatory cells.
Mo Liu, Zhencheng Sun, Fang Liang, Ruizhang Yao, Lu Yang, Ding Nan, Jing Yang, Qingjun Su, Xuehua Liu   +8 more
doaj   +1 more source

Case report: Successful treatment of hyperbaric oxygen for radiation-induced hemorrhagic cystitis in a 95-year-old patient with bladder cancer

Frontiers in Oncology
BackgroundSevere radiation-induced hemorrhagic cystitis (RHC) may ultimately require radical cystectomy. High-quality clinical evidence exists regarding the impact of hyperbaric oxygen therapy (HBOT) on RHC.
Li Lin, Li Lin, Man He, Yanyan Zeng, Xiaoxiao Ni, Yequn Guo, Xiaojuan Xie, Lingling Sun, Huai Huang   +8 more
doaj   +1 more source

Mir-573 regulates cell proliferation and apoptosis by targeting Bax in human degenerative disc cells following hyperbaric oxygen treatment

Journal of Orthopaedic Surgery and Research, 2021
Background MicroRNA (miRNA) plays a vital role in the intervertebral disc (IVD) degeneration. The expression level of miR-573 was downregulated whereas Bax was upregulated notably in human degenerative nucleus pulposus cells.
Song-Shu Lin, Chi-Chien Niu, Li-Jen Yuan, Tsung-Ting Tsai, Po-Liang Lai, Kowit-Yu Chong, Kuo-Chen Wei, Chiung-Yin Huang, Meng-Ling Lu, Chuen-Yung Yang, Steve W. N. Ueng   +10 more
doaj   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Hyperbaric oxygen therapy services at the Pamela Youde Nethersole Eastern Hospital hyperbaric oxygen therapy Center: A retrospective epidemiological study

Hong Kong Journal of Emergency Medicine
Introduction The aim of this retrospective epidemiological study is to analyze the characteristics and caseload of patients treated at the Pamela Youde Nethersole Eastern Hospital (PYNEH) hyperbaric oxygen therapy (HBOT) Center in Hong Kong from 2018 to ...
Kin Bong Tang, Hiu Kwan Suen, Wing Wa Yan   +2 more
doaj   +1 more source

Hyperbaric oxygen therapy: a possible choice for patients with resistant thin endometrium during frozen embryo transfer treatments

Reproductive Biology and Endocrinology, 2023
Background Thin endometrium is considered suboptimal for embryo implantation, leading to compromised pregnancy rates without effective therapies. While some studies have reported promoted endometrial growth after a period of hyperbaric oxygen therapy ...
Jingjing Chen, Fangling Huang, Jing Fu, Jianjuan Zhao, Jinsheng Li, Zhengrong Peng, Jing Zhao, Bin Xu, Shuyi Li, Qiong Zhang, Shaolin Liang, Yanping Li   +11 more
doaj   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

VIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro, Kellie Fortune, Eimear Daly, Luca McCann, Merhan Soltan, Seamus Sreenan, Fabio Quondamatteo   +6 more
wiley   +1 more source

Prenatal Environmental Hypoxia Enhances Adult Hypoxia Tolerance in Brandt's Voles (Lasiopodomys brandtii): Behavioral and Transcriptomic Insights

Integrative Zoology, EarlyView.
Prenatal hypoxia enhances adult hypoxia tolerance in Brandt's voles, preserving cognitive and memory functions. Transcriptomic analysis reveals adaptive changes in energy metabolism, oxygen transport, and neuroprotective mechanisms, highlighting developmental plasticity.
Mengyang Li, Congcong Qiao, Xiujuan Li, Maolin Huang, Zhenlong Wang, Luye Shi   +5 more
wiley   +1 more source

Air embolism secondary to suspected lymphatic tissue disruption with severe exercise‐induced pulmonary haemorrhage

Equine Veterinary Education, EarlyView.
Summary Air embolism is rare in horses and typically associated with complications following intravenous catheterisation or other medical procedures. Exercise‐induced pulmonary haemorrhage (EIPH) is common in racehorses but not usually associated with air embolism. This report describes a case of air embolism in a 4‐year‐old Thoroughbred with EIPH. The
J. Wittenberg, K. Drozdzewska, K. Landmann, A. Voß, K. Kunze, D. Rutenberg, A. D. Gruber, H. Gehlen   +7 more
wiley   +1 more source