Results 41 to 50 of about 39,690 (273)

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond

BMEMat, EarlyView.
Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad, Wan Nurhidayah Wan Hanaffi, Anas Islam, Aimen Salman, Mohd Muazzam Khan, Faiyaz Shakeel, Qiang Cai, Xiaojun Cai, Quazi T. H. Shubhra   +8 more
wiley   +1 more source

Nomogram for Predicting Osteoradionecrosis After Fibula Free Flap for Mandibular Reconstruction

Head &Neck, EarlyView.
ABSTRACT Background Osteoradionecrosis (ORN) is a severe complication following radiotherapy (RT), particularly after mandibular reconstruction with a fibula free flap. Risk prediction remains challenging due to limited data. Methods We conducted a multicenter retrospective study including 294 patients who underwent fibula free flap reconstruction and ...
Andrea Costantino, Bianca Festa, Filippo Marchi, Chung‐Kan Tsao, Raul Pellini, Luca Gazzini, Peter T. Dzięgielewski, Mario Ciniglio, Francesco Mazzola, Luca Calabrese, Antonio Sarno, Giampiero Parrinello, Linda Chow, Jyh‐Kwei Chen, Giorgio Peretti, Armando De Virgilio   +15 more
wiley   +1 more source

The application and perspective of hyperbaric oxygen therapy in acute ischemic stroke: From the bench to a starter?

Frontiers in Neurology, 2022
Stroke has become a significant cause of death and disability globally. Along with the transition of the world's aging population, the incidence of acute ischemic stroke is increasing year by year.
Yujia Yan, Yujia Yan, Xiqiang Zhang, Xingwei An, Xingwei An, Wanpeng Fan, Jingbo Liang, Bin Luo, Hecheng Ren, Ying Huang   +9 more
doaj   +1 more source

Therapie chronischer Wunden mit wassergefiltertem Infrarot A (wIRA) [PDF]

, 2008
The central portion of chronic wounds is often hypoxic and relatively hypothermic, representing a deficient energy supply of the tissue, which impedes wound healing or even makes it impossible.
Daeschlein, Georg, Felbert, Verena von, Hoffmann, Gerd, Mercer, James B., Schumann, Hauke, Strasser, Wolfgang   +5 more
core   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Case report: Consecutive hyperbaric oxygen therapy for delayed post-hypoxic leukoencephalopathy resulting from CHANTER syndrome caused by opioid intoxication

Frontiers in Medicine
Delayed post-hypoxic leukoencephalopathy (DPHL) is a poorly recognized syndrome characterized by neuropsychiatric symptoms following recovery from an acute hypoxic episode.
Naoto Jingami, Naoto Jingami, Naoto Jingami, Kosai Cho, Takayuki Nitta, Miwa Takatani, Katsuya Kobayashi, Ryo Takenaka, Naoko Sugita, Shigeru Ohtsuru, Shigeru Ohtsuru   +10 more
doaj   +1 more source

NASA Light Emitting Diode Medical Applications from Deep Space to Deep Sea [PDF]

, 2001
This work is supported and managed through the NASA Marshall Space Flight Center-SBIR Program. LED-technology developed for NASA plant growth experiments in space shows promise for delivering light deep into tissues of the body to promote wound healing ...
Buchmann, Ellen V., Caviness, James, Cevenini, Vita, Chen, Gina, Cwiklinski, Joan, Gould, Lisa J., Hodgson, Brian D., Ignatius, Ron, Kane, Mary P., Martin, Todd, Meyer, Glenn A., Stinson, Helen, Turner, Scott G., Whelan, Harry T., Whelan, Noel T.   +14 more
core   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

Ibrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard, Vivian Kapio Abem, Sagor Kumar Roy   +2 more
wiley   +1 more source

Efficacy of Hyperbaric Oxygen Therapy for Radiation Cystitis—A Local Center Experience

Hong Kong Journal of Emergency Medicine
Introduction Radiation cystitis is a debilitating condition with no standardized management protocol, significantly impairing the quality of life of patients with cancer treated with pelvic radiotherapy. Hyperbaric oxygen therapy (HBOT) is recognized for
W. C. Yu, A. Siu, W. W. Yan, K. B. Tang
doaj   +1 more source