Results 161 to 170 of about 58,406 (311)
ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapies have revolutionized the treatment of hematological malignancies, achieving high response rates in patients with relapsed or refractory disease. Despite these benefits, CAR‐T cell therapies are associated with unique toxicities, including cytokine release syndrome (CRS), immune effector cell ...
Livia Donzelli +7 more
wiley +1 more source
ABSTRACT The combination of tafasitamab and lenalidomide (tafa‐lena) has demonstrated efficacy in relapsed/refractory diffuse large B‐cell lymphoma (R/R DLBCL), as evidenced by the L‐MIND study. To investigate the therapeutic potential and safety profile of tafa‐lena in real‐life, we conducted a national multicentric retrospective study.
Lisa Argnani +34 more
wiley +1 more source
ABSTRACT Background and Aims Bilirubin, an antioxidant and anti‐inflammatory agent, has been shown to negatively correlate with adiposity. However, the extent to which adiposity level influences total bilirubin (TBili) concentration remains unclear. We sought to evaluate the associations of body mass index (BMI; kg/m²) and waist circumference (WC) with
Trishna Parikh +6 more
wiley +1 more source
Anti‐Tubercular Drug‐Induced Liver Injury: Current Understanding and Emerging Directions
ABSTRACT Most common adverse effect causing cessation of anti‐tubercular treatment (ATT) is drug‐induced liver injury (DILI) which is unpredictable due to its idiosyncratic nature. ATT is the most common cause of DILI and drug‐induced acute liver failure (ALF) in South East Asia.
Shubham Prasad +3 more
wiley +1 more source
Hyperbilirubinemia and appendicular perforation peritonitis
Rajandeep Singh Gupta +2 more
openalex +2 more sources
ABSTRACT Long‐chain fatty acid oxidation disorders (lcFAODs) are genetic disorders of energy metabolism that are associated with a risk of metabolic decompensation, especially during catabolic episodes. With improvement in diagnostics and treatment, more women with lcFAODs now reach child‐bearing age.
Sarah C. Grünert +27 more
wiley +1 more source
ABSTRACT Cell trafficking disorders(CTDs) are rare, heterogeneous inherited conditions marked by impaired intracellular transport mechanisms such as vesicular trafficking, cytoskeletal dynamics, and organelle interactions. Although clinical awareness is increasing, CTDs are often underdiagnosed due to phenotypic overlap with mitochondrial, lysosomal ...
Merve Yoldaş Çelik +6 more
wiley +1 more source

