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Technical Report: Diagnosis and Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation.

Pediatrics, 2022
CONTEXT Severe hyperbilirubinemia is associated with kernicterus. Informed guidance on hyperbilirubinemia management, including preventive treatment thresholds, is essential to safely minimize neurodevelopmental risk.
J. Slaughter, A. Kemper, T. Newman
semanticscholar   +1 more source

Clinical Practice Guideline Revision: Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation.

Pediatrics, 2022
than 80% of newborn infants will have some degree of jaundice. 1,2 Careful monitoring of all newborn infants and the application of appropriate treatments are essential, because high bilirubin concentrations can cause acute bilirubin encephalopathy and ...
M. M. M. F. Alex R. Kemper   +18 more
semanticscholar   +1 more source

Neonatal hyperbilirubinemia and the role of unbound bilirubin

Journal of Maternal-Fetal & Neonatal Medicine, 2021
Background Neonatal jaundice occurs in more than 80% of newborn infants. Although mild jaundice is physiologic and possibly neuroprotective, severe hyperbilirubinemia can lead to neurologic dysfunction and death. Hyperbilirubinemia is due to an imbalance
T. Hegyi, A. Kleinfeld
semanticscholar   +1 more source

Hyperbilirubinemia and Kernicterus [PDF]

open access: possibleClinics in Perinatology, 2006
This article describes new findings concerning the basic science of bilirubin neurotoxicity, new considerations of the definition of clinical kernicterus, and new and useful tools to diagnose kernicterus in older children, and discusses treatments for kernicterus beyond the newborn period and why proper diagnosis is important.
Steven M. Shapiro   +2 more
openaire   +2 more sources

Neonatal Indirect Hyperbilirubinemia.

NeoReviews, 2020
Neonatal indirect hyperbilirubinemia (IHB) is caused by an imbalance in bilirubin production and elimination. Approximately 60% of term and 80% of preterm infants develop jaundice in the first week of age.
Nicole B. Anderson, K. Calkins
semanticscholar   +1 more source

The Management of Hyperbilirubinemia

Clinics in Perinatology, 1984
When pre-established "safe" limits of serum bilirubin are exceeded, or when hyperbilirubinemia is present in association with other conditions such as prematurity with respiratory distress, asphyxia, or neonatal infections, the need to lessen the risk of bilirubin encephalopathy requires specific and effective interventions to lower the unconjugated or
Leo Stern, William J. Cashore
openaire   +3 more sources

The Issues of Hyperbilirubinemia

Pediatrics, 1995
"Tis with our judgments as our watches, none go just alike, yet each believes his own." Alexander Pope An Essay on Criticism, 1711. The practice parameter published recently by the American Academy of Pediatrics Provisional Committee for Quality Improvement and Subcommittee on Hyperbilirubinemia1 introduces ...
Daniel S. Seidman, David K. Stevenson
openaire   +3 more sources

Hyperbilirubinemia in the Newborn

Pediatrics In Review, 2011
After completing this article, readers should be able to: 1. List the risk factors for severe hyperbilirubinemia. 2. Distinguish between physiologic jaundice and pathologic jaundice of the newborn. 3. Recognize the clinical manifestations of acute bilirubin encephalopathy and the permanent clinical sequelae of kernicterus.4.
Bryon J. Lauer, Nancy D. Spector
openaire   +3 more sources

Treatment practices and implementation of guidelines for hyperbilirubinemia and rebound hyperbilirubinemia

Journal of Neonatal-Perinatal Medicine, 2022
BACKGROUND: Hyperbilirubinemia (HB), defined as elevated total serum bilirubin (TSB) levels, commonly affects neonates and requires prompt treatment to prevent neurological complications. Up to 10%of neonates experience rebound hyperbilirubinemia (RHB), requiring re-initiation of treatment.
V. So, F. Khurshid
openaire   +3 more sources

Neonatal Hyperbilirubinemia

The Journal of Perinatal & Neonatal Nursing, 2006
Evidence of bilirubin-related brain damage has been reported in infants with kernicterus discharged as healthy from well-baby nurseries. Lapses in care have been attributed as root causes for kernicterus in an era when there should be no barriers to safe and effective bilirubin reduction strategies.
Ann, Schwoebel, Susan, Gennaro
openaire   +3 more sources

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