Results 31 to 40 of about 198,923 (186)

Incidence and Risk Factors of Serious Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia: A CYP‐C Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers, Chantal Éthier, Caroline Laverdière, Nathalie Alos, Thai Hoa Tran, Marie‐Claude Pelland‐Marcotte   +5 more
wiley   +1 more source

Asymptotic theory of the hyperbolic boundary layer in shells of revolution at shock edge loading of the tangential type [PDF]

Известия Саратовского университета. Новая серия: Математика. Механика. Информатика
The present work is devoted to the construction of asymptotically optimized equations of the hyperbolic boundary layer in thin shells of revolution in the vicinity of the dilation wave front at shock edge loading of the tangential type.
Kirillova, Irina V.
doaj   +1 more source

Towards the theory of integrable hyperbolic equations of third order

, 2012
The examples are considered of integrable hyperbolic equations of third order with two independent variables. In particular, an equation is found which admits as evolutionary symmetries the Krichever--Novikov equation and the modified Landau--Lifshitz ...
A B Shabat, Bobenko A I, Courant R, Degasperis A Procesi M Degasperis A Gaeta G, Hone A N W, Ivanov R I, Shabat A B, Svinolupov S I, V E Adler, Wolfram S, Zhiber A V, Zhiber A V, Zhiber A V, Zhiber A V, Zhiber A V   +14 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Wave and Dirac equations on manifolds

, 2018
We review some recent results on geometric equations on Lorentzian manifolds such as the wave and Dirac equations. This includes well-posedness and stability for various initial value problems, as well as results on the structure of these equations on ...
Andersson, Lars, Baer, Christian
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The Goursat-type problem for a hyperbolic equation and system of third order hyperbolic equations

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2019
In the first part of this study, the well-posed Goursat-type problem is considered for the hyperbolic differential equation of the third order with non-multiple characteristics.
Aleksandr Anatol'evich Andreev, Juliya Olegovna Yakovleva   +1 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The characteristic problem for the system of the general hyperbolic differential equations of the third order with nonmultiple characteristics

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2013
We consider the well-posed characteristic problem for the system of the general hyperbolic differential equations of the third order with nonmultiple characteristics. The solution of this problem is constructed in an explicit form.
Aleksandr Anatol'evich Andreev, Juliya Olegovna Yakovleva   +1 more
doaj   +1 more source

Extending the lifetime of 3D black hole computations with a new hyperbolic system of evolution equations [PDF]

, 2001
We present a new many-parameter family of hyperbolic representations of Einstein's equations, which we obtain by a straightforward generalization of previously known systems.
A. Abrahams, A. Anderson, A. Anderson, A. Gullstrand, C. Bona, C. Bona, C. Gundlach, F.B. Estabrook, G. Yoneda, G. Yoneda, G. Yoneda, G.B. Cook, H. Friedrich, H. Friedrich, H. Shinkai, J.M. Stewart, J.W. York, Jr., K. Martel, L.E. Kidder, Lawrence E. Kidder, M. Alcubierre, M. Alcubierre, M. Alcubierre, M. Alcubierre, M.A. Scheel, M.A.G. Bonilla, M.H.P.M. van Putten, M.S. Iriondo, Mark A. Scheel, O. Brodbeck, P. Painlevé, R. Arnowitt, R.A. Matzner, R.L. Marsa, S. Brandt, S. Frittelli, S. Frittelli, S. Frittelli, Saul A. Teukolsky, T.W. Baumgarte, Y. Choquet-Bruhat   +40 more
core   +3 more sources