Results 271 to 280 of about 279,482 (318)

In Vitro Monitoring of Babesia microti Infection Dynamics in Whole Blood Microenvironments

open access: yesAdvanced Science, EarlyView.
Here, an open microfluidic platform termed “µ‐Blood” is reported for real‐time, continuous monitoring of Babesia microti infection dynamics in vitro. µ‐Blood allows direct interrogation of whole blood with preserved integrity of the original whole blood microenvironment through an extended period (e.g., 72 h with mouse red blood cells) ex vivo. µ‐Blood
Chao Li   +4 more
wiley   +1 more source

SCORCH2: A Generalized Heterogeneous Consensus Model for High‐Enrichment Interaction‐Based Virtual Screening

open access: yesAdvanced Science, EarlyView.
Researchers developed SCORCH2, an advanced machine‐learning scoring function for virtual screening that combines two complementary XGBoost models to re‐evaluate protein‐ligand binding plausibility. The method demonstrates superior performance on standard benchmarks, shows excellent generalization to previously unseen protein targets, and provides ...
Lin Chen   +3 more
wiley   +1 more source

Multiscale Cell–Cell Interactive Spatial Transcriptomics Analysis

open access: yesAdvanced Science, EarlyView.
In this study, we present the MultiScale Cell‐Cell Interactive Spatial Transcriptomics Analysis method, which unites the strengths of spatially resolved deep learning techniques with a topological representation of multi‐scale cell‐cell similarity relations.
Sean Cottrell, Guo‐Wei Wei
wiley   +1 more source

Dynamic Synthesis of Multi‐Modal Representations for CITE‐seq Data Integration and Analysis

open access: yesAdvanced Science, EarlyView.
The accurate integration of CITE‐seq modalities faces challenges due to complex RNA‐protein nonlinear interactions and computational inefficiencies. A lightweight framework that adaptively fuses RNA and ADT modalities, and refines them through fine‐grained learning is developed to address this issue.
Yinan Shi   +5 more
wiley   +1 more source

Robotic Materials With Bioinspired Microstructures for High Sensitivity and Fast Actuation

open access: yesAdvanced Science, EarlyView.
In the review paper, design rationale and approaches for bioinspired sensors and actuators in robotics applications are presented. These bioinspired microstructure strategies implemented in both can improve the performance in several ways. Also, recent ideas and innovations that embed robotic materials with logic and computation with it are part of the
Sakshi Sakshi   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy