Results 41 to 50 of about 284,848 (317)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
On the Superstability Related with the Trigonometric Functional Equation
Advances in Difference Equations, 2009 We will investigate the superstability of the (hyperbolic) trigonometric functional equation from the following functional equations: , , , , which can be considered the mixed functional equations of the sine function and cosine function, of the ...
Kim GwangHui
doaj +2 more sources
Construction of nearly hyperbolic distance on punctured spheres
, 2017 We define a distance function on the bordered punctured disk ...
Sugawa, Toshiyuki, Zhang, Tanran
core +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
A local saddle point for the hyperbolic augmented Lagrangian function
Examples and CounterexamplesIn this paper, we study the hyperbolic augmented Lagrangian function, which is based on the hyperbolic penalty function. We ensure the existence of a local saddle point for the hyperbolic augmented Lagrangian function in nonconvex constrained ...
Lennin Mallma Ramirez +3 more
doaj +1 more source
Comptes Rendus. Mécanique, 2023 This note is concerned with the dynamics of 1D temperature waves generated by time modulation of a boundary heat flux. It demonstrates how a certain temporal transfer function of both parabolic and low frequency hyperbolic interfacial temperature waves ...
Haidar, Nassar
doaj +1 more source
Hyperbolically convex functions [PDF]
Annales Polonici Mathematici, 1994 A region \(\Omega\subset D= \{z\mid | z|< 1\}\) is called hyperbolically convex if for all \(a,b\subset \Omega\) the hyperbolic geodesic connecting \(a\) and \(b\) lies in \(\Omega\). A holomorphic function \(f: D\to D\) is called hyperbolically convex if it is univalent, \(f(D)\) is hyperbolically convex and \(f(0)= 0\), \(f'(0)> 0\).
Ma, Wancang, Minda, David
openaire +2 more sources
Probing hyperbolic polaritons using infrared attenuated total reflectance micro-spectroscopy
, 2018 Hyperbolic polariton modes are highly appealing for a broad range of applications in nanophotonics, including surfaced enhanced sensing, sub-diffractional imaging and reconfigurable metasurfaces.
Caldwell, Joshua D. +9 more
core +1 more source