Results 131 to 140 of about 379,230 (325)

Spatiotemporal Characterization of the Functional MRI Latency Structure with Respect to Neural Signaling and Brain Hierarchy

open access: yesAdvanced Science, EarlyView.
Resting‐state fMRI captures intrinsic brain activity, yet the physical significance of latency structures remains unclear. In this study, the spatiotemporal properties of fMRI‐derived latency structures are examined by linking them to biophysical model‐based neural functions, intrinsic neural timescales, and functional gradients.
Hyoungshin Choi   +5 more
wiley   +1 more source

Harmonic-hyperbolic geometric flow

open access: yesElectronic Journal of Differential Equations, 2017
In this article we study a coupled system for hyperbolic geometric flow on a closed manifold M, with a harmonic flow map from M to some closed target manifold N. Then we show that this flow has a unique solution for a short-time.
Shahroud Azami
doaj  

On the volumes of complex hyperbolic manifolds

open access: yesDuke Mathematical Journal, 1996
In this paper, the authors give some estimates for the volume of a complete locally symmetric Riemannian manifold of negative curvature. The main results are the following: Theorem 1. Let \(M\) be a closed complex hyperbolic surface. Then the smallest volume for such an \(M\) is \(8\pi^2\) and the smallest Euler characteristic is 3. Theorem 2. Let \(M\)
Hersonsky, Sa’ar, Paulin, Frédéric
openaire   +4 more sources

SCRIPT: Predicting Single‐Cell Long‐Range Cis‐Regulation Based on Pretrained Graph Attention Networks

open access: yesAdvanced Science, EarlyView.
SCRIPT is a novel method inferring single‐cell cis‐regulatory relationships (CRRs) from transcriptomic and chromatin accessibility data. SCRIPT incorporates two key innovations: graph causal attention networks supported by empirical CRR evidence, and representation learning enhanced through pretraining on atlas‐scale single‐cell data.
Yu Zhang   +13 more
wiley   +1 more source

Singularly perturbed semilinear Neumann problem with non-normally hyperbolic critical manifold

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2010
In this paper, we investigate the problem of existence and asymptotic behavior of the solutions for the nonlinear boundary value problem \begin{eqnarray*} \epsilon y''+ky=f(t,y),\quad t\in\langle a,b \rangle, \quad k>0,\quad ...
Robert Vrabel
doaj   +1 more source

Resident Macrophage‐Orchestrated Immune and Fibroblast Interactions in Immune Checkpoint Inhibitor‐Associated Nephrotoxicity

open access: yesAdvanced Science, EarlyView.
Schematic illustration of resident macrophages in Immune checkpoint inhibitor‐associated nephrotoxicity (ICI‐AN). Using an integrated approach (including imaging mass cytometry, transcriptomics, and murine models), this study reveals that resident macrophages drive immune‐stromal interactions in ICI‐AN, promoting fibroblast activation through CXCL9 and
Yanhong Ma   +11 more
wiley   +1 more source

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

open access: yesAdvanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo   +17 more
wiley   +1 more source

Pinching constants for hyperbolic manifolds

open access: yesInventiones Mathematicae, 1987
This paper exhibits very interesting examples of n-manifolds M, \(n\geq 4\), with negative sectional curvature, \(K_ M\).
Gromov, M., Thurston, W.
openaire   +2 more sources

CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery

open access: yesAdvanced Science, EarlyView.
High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu   +14 more
wiley   +1 more source

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