Results 81 to 90 of about 157,678 (311)

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

On the arithmetic of crossratios and generalised Mertens' formulas

open access: yes, 2013
We develop the relation between hyperbolic geometry and arithmetic equidistribution problems that arises from the action of arithmetic groups on real hyperbolic spaces, especially in dimension up to 5.
Parkkonen, Jouni, Paulin, Frédéric
core   +3 more sources

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan   +14 more
wiley   +1 more source

On Mersenne Numbers and their Bihyperbolic Generalizations

open access: yesAnnales Mathematicae Silesianae
In this paper, we introduce Mersenne and Mersenne–Lucas bihyperbolic numbers, i.e. bihyperbolic numbers whose coefficients are consecutive Mersenne and Mersenne–Lucas numbers.
Bród Dorota, Szynal-Liana Anetta
doaj   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto   +12 more
wiley   +1 more source

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

open access: yesArthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette   +13 more
wiley   +1 more source

Algebraic numbers, hyperbolicity, and density modulo one

open access: yesJournal of Number Theory, 2012
We prove the density of the sets of the form ${ _1^m _1^n _1 +...+ _k^m _k^n _k : m,n \in \mathbb N}$ modulo one, where $ _i$ and $ _i$ are multiplicatively independent algebraic numbers satisfying some additional assumptions. The proof is based on analysing dynamics of higher-rank actions on compact abelean groups.
Gorodnik, A, Kadyrov, S
openaire   +3 more sources

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals With Type 2 Diabetes

open access: yesArthritis Care &Research, EarlyView.
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King   +10 more
wiley   +1 more source

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